2023-04-04T20:56:59+03:00[Europe/Moscow] en true <p>wet granulation</p>, <p>hot melt extrusion</p>, <p>damp or liquid material is inserted into a mold and allowed to dry</p>, <p>high pressure applied directly to dry excipients to create tablet</p>, <p>Glidant</p>, <p>lubricant</p>, <p>lactose, mannitol, sorbitol</p>, <p>gelatin, tragacanth</p>, <p>starch, cellulose</p>, <p>stearic acid, talc, waxes</p>, <p>talc, silica</p>, <p>cornstarch, dyes/lakes</p>, <p>does not move</p> flashcards
tablet manufacturing

tablet manufacturing

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  • wet granulation

    -product is dampened and separated into particles prior to tablet compression.

  • hot melt extrusion

    -homogenous and unstable.

  • damp or liquid material is inserted into a mold and allowed to dry

    How are Molded tablets prepared?

  • high pressure applied directly to dry excipients to create tablet

    How are Compressed tablets prepared?

  • Glidant

    -pharmacologically inactive substance used to optimize the flow properties of tablet granulation or powder materials by decreasing inter-particle friction and cohesion

  • lubricant

    -pharmacologically inactive substance added to the formulation to decrease friction between tablet’s surface and the die wall cavity in which the tablet was formed

  • lactose, mannitol, sorbitol

    What are our diluents?

  • gelatin, tragacanth

    What are our binders/ adhesives?

  • starch, cellulose

    What are our disintegrants?

  • stearic acid, talc, waxes

    What are our lubricants?

  • talc, silica

    What are our glidants?

  • cornstarch, dyes/lakes

    What are our colors?

  • does not move

    In the Single Punch tablet press, lower punch ______ during compression.