Hosam Mohamed-
d
Which is most likely related to an antibiotic reaction?
a) type I
b) type II
c) type III
d) type IV
-
48-72 hours
What is the reaction time for a Type IV reaction?
-
d
Type IV reactions are carried out by what type of immune reaction?
a) IgE
b) IgG/IgM- Cell associated
c) IgG/IgM- Soluble antigen
d) T cells
-
d
Which cell is involved in Type I reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast cells
-
a
Which cell is involved in Type II reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast
-
b
Which cell is involved in Type III reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast
-
c
Which cell is involved in Type IV reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast
-
a
Which reaction is IgE mediated?
a) anaphylaxis
b) anaphylactoid
-
HIV patients
Sulfa allergies are most present in who?
-
pens, cephs, carbapenems, vancomycin, clindamycin, daptomycin, fidaxomicin, metronidazole
Which antimicrobials are safe in pregnancy? (8)
-
c
Which antimicrobial is dependent on the trimester the pregnant patient is in?
a) azithromycin
b) oxazolidinones
c) bactrim
d) fidaxomicin
-
d
Which AG is especially dangerous to use on pregnant women?
a) gentamicin
b) tobramicin
c) amikacin
d) streptomycin
-
okay for short-term use
What is our note for Aminoglycosides in pregnancy?
-
avoid in pregnancy
What is our note on Tetracyclines in pregnancy?
-
lipoglycopeptides, oxazolidinones, clarithro, erythro, fq's
Which ab's can we use if the should we avoid/use with caution? (5)
-
b
Which lipoglycopeptides should we especially avoid using in pregnant women?
a) dalbavancin
b) telavancin
c) oritovancin
d) galavancin
-
avoid in 1st trimester and after 32 weeks gestation
What is our note on Bactrim in pregnant women?
-
acyclovir, valacyclovir, famciclovir
Which antivirals are safe in pregnancy? (3)
-
cidofovir, ganciclovir, foscarnet, amantadine, rimantadine
Which antivirals should we avoid/use with caution? (5)
-
a
Which neuraminidase inhibitor can cause hypoglycemia after birth?
a) oseltamivir
b) zanamivir
c) peramivir
d) laniamivir
-
amphotericin
Which antifungal is safe in pregnant women?
-
azoles, echinocandins, flucytosine
Which antifungals should be avoided/used with caution in pregnant women? (3)
-
plasma protein binding, lipophilicity, molecule size
What factors determine if an antimicrobial is transferred through breast milk? (3)
-
increased transfer
High lipophilicity =
-
decreased transfer
High molecular weight =
-
decreased transfer
High plasma protein binding =
-
increased transfer
High milk protein binding =
-
tetracyclines
Which antimicrobials should we avoid in lactating mothers?
-
c
Which azole is the best in terms of breastfeeding?
a) isovuconazole
b) itravuconazole
c) fluconazole
d) posconazole
