d
Which is most likely related to an antibiotic reaction?
a) type I
b) type II
c) type III
d) type IV
48-72 hours
What is the reaction time for a Type IV reaction?
d
Type IV reactions are carried out by what type of immune reaction?
a) IgE
b) IgG/IgM- Cell associated
c) IgG/IgM- Soluble antigen
d) T cells
d
Which cell is involved in Type I reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast cells
a
Which cell is involved in Type II reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast
b
Which cell is involved in Type III reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast
c
Which cell is involved in Type IV reactions?
a) macrophages
b) neutrophils
c) T cells
d) mast
a
Which reaction is IgE mediated?
a) anaphylaxis
b) anaphylactoid
HIV patients
Sulfa allergies are most present in who?
pens, cephs, carbapenems, vancomycin, clindamycin, daptomycin, fidaxomicin, metronidazole
Which antimicrobials are safe in pregnancy? (8)
c
Which antimicrobial is dependent on the trimester the pregnant patient is in?
a) azithromycin
b) oxazolidinones
c) bactrim
d) fidaxomicin
d
Which AG is especially dangerous to use on pregnant women?
a) gentamicin
b) tobramicin
c) amikacin
d) streptomycin
okay for short-term use
What is our note for Aminoglycosides in pregnancy?
avoid in pregnancy
What is our note on Tetracyclines in pregnancy?
lipoglycopeptides, oxazolidinones, clarithro, erythro, fq's
Which ab's can we use if the should we avoid/use with caution? (5)
b
Which lipoglycopeptides should we especially avoid using in pregnant women?
a) dalbavancin
b) telavancin
c) oritovancin
d) galavancin
avoid in 1st trimester and after 32 weeks gestation
What is our note on Bactrim in pregnant women?
acyclovir, valacyclovir, famciclovir
Which antivirals are safe in pregnancy? (3)
cidofovir, ganciclovir, foscarnet, amantadine, rimantadine
Which antivirals should we avoid/use with caution? (5)
a
Which neuraminidase inhibitor can cause hypoglycemia after birth?
a) oseltamivir
b) zanamivir
c) peramivir
d) laniamivir
amphotericin
Which antifungal is safe in pregnant women?
azoles, echinocandins, flucytosine
Which antifungals should be avoided/used with caution in pregnant women? (3)
plasma protein binding, lipophilicity, molecule size
What factors determine if an antimicrobial is transferred through breast milk? (3)
increased transfer
High lipophilicity =
decreased transfer
High molecular weight =
decreased transfer
High plasma protein binding =
increased transfer
High milk protein binding =
tetracyclines
Which antimicrobials should we avoid in lactating mothers?
c
Which azole is the best in terms of breastfeeding?
a) isovuconazole
b) itravuconazole
c) fluconazole
d) posconazole