renin

The initial stimulus for the release of renin is a __________ in _________ ________ _________

extrinsic control mechanisms

__________ ____ of the juxtaglomerular complex of the _________ release ______ through three different pathways

extrinsic control mechanisms

Release of renin (1/3)

_______________ ______ in blood vessels of systemic circulation. renal __________ _____ activate receptors that signal _________ ____ to release ______

extrinsic control mechanisms

Release of renin (2/3)

low __________ __________ of __________ __________ reduces glomerular __________ ____, the low __________ _______ in slower ______ ________ filtrate detected by ________ _________ signals _________ ____ to release ______

extrinsic control mechanisms

Release of renin (3/3)

granular cells act as ________________, a decrease in _______ ________ _________ reduces ________ in granular cell __________ and stimulates them to release _______

___________________ is produced in the liver

_______ catalyzes the conversion which converts _____________ into _______________ __

______________________ is found in the lungs and converts Angiotensin I into Angiotensin II

extrinsic control mechanisms

Angiotensin II affects blood pressure in 3 ways

1. _____________ secretion by the __________ _________ causes sodium _____________ and potassium ___________ by _______ ________ _______, ________ follows the sodium which increases _______ volume resulting in increased ________ _________ _________

Angiotensin II affects blood pressure in 3 ways

2. the baroreceptor reflex also causes ______________ of _________ _________ increases _________ _________ resulting in increased _________ _____ _________

this is the only _______ _________ _________

extrinsic control mechanisms

Angiotensin II affects blood pressure in 3 ways

3. stimulation of the _________ _________ ________ releases __________ __________ affecting the _________ _________ of the kidneys to increase _____ _____________ and increases

the _______ ____________ __________ mechanism is an example of ___________ _________ ________

GFR is controlled by changing the single variable of __________ ________ ___________

an increase in ____ increases ________ _______ which reduces ________ _________ and _________ _________

intrinsic controls through ________ _______________ allow the kidneys to adjust its own __________ to _______ ______ despite ____________ in systemic arterial _______ _________, they occur when mean arterial pressure is between ___ and _____ mm

Intrinsic controls/renal autoregulation

the stimulus for the _____________ _____________ ___ _________________ is a decrease in _________ _________ of _________ __________ which lowers the GFR, the decreased ________ of smooth muscle walls in afferent arterioles induces ___________ arteriole ____________ to raise the ____

Intrinsic controls/renal autoregulation

the stimulus for the ____________________ ___________ ___ __________ is a decrease in _____ detected a decrease in ____ content of the ________ in the ascending nephron loop which triggers _________ ________ cells to induce ________ arteriole _____________

extrinsic controls occur when mean arterial pressure falls far outside the normal range either _____ or _______ mm hg