2023-12-05T04:34:08+03:00[Europe/Moscow] en true <p>b</p>, <p>a</p>, <p>a</p>, <p>false</p>, <p>pain/inflammation</p>, <p>NSAIDs, acetaminophen, glucocorticoids, tramadol, capsaicin, duloxetine </p>, <p>hyaluronic acid, chondroitin, glucosamine</p>, <p>b</p>, <p>enhance chondrocyte HA synthesis, prevent degradation of cartilage/promote regeneration, reduce inflammatory mediators/MMP</p>, <p>a,c</p>, <p>a</p>, <p>c</p>, <p>c</p>, <p>a</p>, <p>knees, hips, hands</p>, <p>Patient history, physical examination, radiologic evaluation</p>, <p>a</p>, <p>b</p>, <p>nonpharmacologic treatment </p>, <p>acetaminophen </p>, <p>NSAIDs(topical or oral), capsaicin, tramadol </p>, <p>topical NSAID</p> flashcards
Pharmacology of Osteoarthritis

Pharmacology of Osteoarthritis

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  • b

    Which disease is caused by inflammation?

    a) osteoarthritis

    b) Rheumatoid Arthritis

  • a

    Which disease is caused by cartilage degradation?

    a) osteoarthritis

    b) Rheumatoid Arthritis

  • a

    Which results in bone erosion?

    a) osteoarthritis

    b) Rheumatoid Arthritis

  • false

    It is possible to prevent Osteoarthritis. T/F?

  • pain/inflammation

    When treating Osteoarthritis, what symptoms are we trying to manage?

  • NSAIDs, acetaminophen, glucocorticoids, tramadol, capsaicin, duloxetine

    What can we use to treat the symptoms of OA? (5)

  • hyaluronic acid, chondroitin, glucosamine

    Which OTC products can we use to treat OA? (3)

  • b

    Which provides visco-supplementation to reduce pain and improve joint lubrication?

    a) chondroitin

    b) hyaluronic acid

    c) glucosamine

  • enhance chondrocyte HA synthesis, prevent degradation of cartilage/promote regeneration, reduce inflammatory mediators/MMP

    What are the benefits of Hyaluronic Acid? (3)

  • a,c

    Which are the structural components of cartilage?

    a) chondroitin

    b) hyaluronic acid

    c) glucosamine

  • a

    Which is found in porcine/bovine trachea or fish/shark cartilage?

    a) chondroitin

    b) hyaluronic acid

    c) glucosamine

  • c

    Which is found in shellfish and should be avoided in patients with severe shellfish allergy?

    a) chondroitin

    b) hyaluronic acid

    c) glucosamine

  • c

    Which stimulates chondrocytes and synoviocytes?

    a) chondroitin

    b) hyaluronic acid

    c) glucosamine

  • a

    Which inhibit cartilage degradation & bone resorption?

    a) chondroitin

    b) hyaluronic acid

    c) glucosamine

  • knees, hips, hands

    Which bones are most commonly affected in OA? (3)

  • Patient history, physical examination, radiologic evaluation

    Which are required for a diagnosis of OA? (3)

  • a

    Which is a bony growth on the middle joint of the finger?

    a) Bouchard's nodes

    b) Heberden's nodes

  • b

    Which is a bony growth on the joint closest to the fingernail?

    a) Bouchard's nodes

    b) Heberden's nodes

  • nonpharmacologic treatment

    What is the main treatment for OA?

  • acetaminophen

    What is 1st line for Hip OA?

  • NSAIDs(topical or oral), capsaicin, tramadol

    What is 1st line for Hand OA? (3)

  • topical NSAID

    What is 1st line for Knee OA?