b
Which disease is caused by inflammation?
a) osteoarthritis
b) Rheumatoid Arthritis
a
Which disease is caused by cartilage degradation?
a) osteoarthritis
b) Rheumatoid Arthritis
a
Which results in bone erosion?
a) osteoarthritis
b) Rheumatoid Arthritis
false
It is possible to prevent Osteoarthritis. T/F?
pain/inflammation
When treating Osteoarthritis, what symptoms are we trying to manage?
NSAIDs, acetaminophen, glucocorticoids, tramadol, capsaicin, duloxetine
What can we use to treat the symptoms of OA? (5)
hyaluronic acid, chondroitin, glucosamine
Which OTC products can we use to treat OA? (3)
b
Which provides visco-supplementation to reduce pain and improve joint lubrication?
a) chondroitin
b) hyaluronic acid
c) glucosamine
enhance chondrocyte HA synthesis, prevent degradation of cartilage/promote regeneration, reduce inflammatory mediators/MMP
What are the benefits of Hyaluronic Acid? (3)
a,c
Which are the structural components of cartilage?
a) chondroitin
b) hyaluronic acid
c) glucosamine
a
Which is found in porcine/bovine trachea or fish/shark cartilage?
a) chondroitin
b) hyaluronic acid
c) glucosamine
c
Which is found in shellfish and should be avoided in patients with severe shellfish allergy?
a) chondroitin
b) hyaluronic acid
c) glucosamine
c
Which stimulates chondrocytes and synoviocytes?
a) chondroitin
b) hyaluronic acid
c) glucosamine
a
Which inhibit cartilage degradation & bone resorption?
a) chondroitin
b) hyaluronic acid
c) glucosamine
knees, hips, hands
Which bones are most commonly affected in OA? (3)
Patient history, physical examination, radiologic evaluation
Which are required for a diagnosis of OA? (3)
a
Which is a bony growth on the middle joint of the finger?
a) Bouchard's nodes
b) Heberden's nodes
b
Which is a bony growth on the joint closest to the fingernail?
a) Bouchard's nodes
b) Heberden's nodes
nonpharmacologic treatment
What is the main treatment for OA?
acetaminophen
What is 1st line for Hip OA?
NSAIDs(topical or oral), capsaicin, tramadol
What is 1st line for Hand OA? (3)
topical NSAID
What is 1st line for Knee OA?