Hosam Mohamed-
M3G, M6G
What are the metabolites of Morphine? (2)
-
a
Which metabolite can cause seizures?
a) M3G
b) M6G
-
b
Which metabolite is 6x more potent for analgesia?
a) M3G
b) M6G
-
b
Which blocks NMDA and monoamine reuptake proteins?
a) Fentanyl
b) Methadone
c) Meperidine
d) Levorphanol
-
b
Which can be used in opioid rotation to reduce tolerance?
a) Fentanyl
b) Methadone
c) Meperidine
d) Levorphanol
-
false
The fentanyl derivatives have a longer duration of action than Fentanyl. T/F?
-
Sufentanil, Fentanyl, Alfentanil
Rank these in terms of potency. Alfentanil, Fentanyl, Sufentail.
-
b
Which is widely used in treating opioid abuse?
a) Fentanyl
b) Methadone
c) Meperidine
d) Levorphanol
-
K & delta
Hydromorphone and Oxymorphone have affinity for _____ & _____ receptors.
-
c
Which has the longest half-life?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
-
a
Which resembles morphine in action?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
-
b
Which has antimuscarinic and negative inotropic effects?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
-
b
Which has a metabolite that can cause seizures?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
-
d
Which has an extremely short half-life and is good for anesthesia?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
-
b
Which is a KOR agonist with with weak MOR antagonism?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
-
a
Which is a strong KOR agonist & strong MOR antagonist?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
-
women
Agents that act through KORs are more effective in _______.
-
a
Which drug has a ceiling effect?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
-
c
Which is the most sedative?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
-
a
Which only acts in the periphery?
a) Loperamide
b) Diphenoxylate
-
b
Which is used in combination with Atropine?
a) Loperamide
b) Diphenoxylate
-
b
Which is insoluble in aqueous solutions to decrease abuse potential?
a) Loperamide
b) Diphenoxylate
