M3G, M6G
What are the metabolites of Morphine? (2)
a
Which metabolite can cause seizures?
a) M3G
b) M6G
b
Which metabolite is 6x more potent for analgesia?
a) M3G
b) M6G
b
Which blocks NMDA and monoamine reuptake proteins?
a) Fentanyl
b) Methadone
c) Meperidine
d) Levorphanol
b
Which can be used in opioid rotation to reduce tolerance?
a) Fentanyl
b) Methadone
c) Meperidine
d) Levorphanol
false
The fentanyl derivatives have a longer duration of action than Fentanyl. T/F?
Sufentanil, Fentanyl, Alfentanil
Rank these in terms of potency. Alfentanil, Fentanyl, Sufentail.
b
Which is widely used in treating opioid abuse?
a) Fentanyl
b) Methadone
c) Meperidine
d) Levorphanol
K & delta
Hydromorphone and Oxymorphone have affinity for _____ & _____ receptors.
c
Which has the longest half-life?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
a
Which resembles morphine in action?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
b
Which has antimuscarinic and negative inotropic effects?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
b
Which has a metabolite that can cause seizures?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
d
Which has an extremely short half-life and is good for anesthesia?
a) Levorphanol
b) Meperidine
c) Fentanyl
d) Remifentanil
b
Which is a KOR agonist with with weak MOR antagonism?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
a
Which is a strong KOR agonist & strong MOR antagonist?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
women
Agents that act through KORs are more effective in _______.
a
Which drug has a ceiling effect?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
c
Which is the most sedative?
a) Nalbuphine
b) Pentazocine
c) Butorphanol
a
Which only acts in the periphery?
a) Loperamide
b) Diphenoxylate
b
Which is used in combination with Atropine?
a) Loperamide
b) Diphenoxylate
b
Which is insoluble in aqueous solutions to decrease abuse potential?
a) Loperamide
b) Diphenoxylate