Hosam Mohamed-
relievers/rescue drugs
-used for treating acute symptoms.
-
controllers/maintenance
-control the inflammatory/remodeling response
-
LT antagonists, theophylline, LAMA
What are our add-ons? (3)
-
histamine, leukotrienes, prostaglandins
IgE-induced mast cell degranulation results in the production of what
inflammatory mediators? (3)
-
SABA, ICS/formo, systemic steroids, SABA/SAMA
What are our relievers? (4)
-
ICS, ICS/LABA, mAB
What are our controllers?(3)
-
c
Which prevents the binding of IgE to mast cells?
a) Mepolizumab
b) Benralizumab
c) Omalizumab
d) Tezepelumab
e) Dupilumab
f) Reslizumab
-
e
Which is an IL-4Ra ab?
a) Mepolizumab
b) Benralizumab
c) Omalizumab
d) Tezepelumab
e) Dupilumab
f) Reslizumab
-
a,f
Which are IL-5 blockers?
a) Mepolizumab
b) Benralizumab
c) Omalizumab
d) Tezepelumab
e) Dupilumab
f) Reslizumab
-
b
Which is a IL-5 receptor blocker?
a) Mepolizumab
b) Benralizumab
c) Omalizumab
d) Tezepelumab
e) Dupilumab
f) Reslizumab
-
LOX
Inhibition of ______ enzyme decreases the synthesis of leukotrienes.
-
thymic stromal lymphopoietin
-activates the first steps of the inflammatory cascade in asthma.
-
ionotropic; chronotropic
Theophylline has a positive _____ & _____ effect.
-
levalbuterol
__________ is a single enantiomer SABA.
-
c
Which has a BBW for anaphylaxis?
a) Mepolizumab
b) Benralizumab
c) Omalizumab
d) Tezepelumab
e) Dupilumab
f) Reslizumab
-
mepolizumab, dupilumab, reslizumab
Which mABs are indicated for eosinophilic asthma? (3)
-
omalizumab
Which is indicated for allergic asthma?
