2023-10-14T03:12:50+03:00[Europe/Moscow] en true <p>sympathomimetics that stimulate a1 receptors in the nasal mucosa causing vasoconstriction </p>, <p>vasodilation; vasoconstriction </p>, <p>phenylephrine, oxymetazoline </p>, <p>Rhinitis medicamentosa </p>, <p>b</p>, <p>a</p>, <p>b</p>, <p>e</p>, <p>b</p>, <p>d</p>, <p>defensive; underlying cause </p>, <p>c</p>, <p>c</p>, <p>d</p>, <p>b</p>, <p>b</p>, <p>CYP2D6</p>, <p>a</p>, <p>increases the volume; reduces viscosity </p>, <p>Benzonatate, codeine, dextromethorphan </p>, <p>guaifenesin </p>, <p>pseudoephedrine, phenylephrine </p>, <p>medullary cough center </p>, <p>b</p> flashcards
Pharmacology (Decongestants & Antitussives)

Pharmacology (Decongestants & Antitussives)

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  • sympathomimetics that stimulate a1 receptors in the nasal mucosa causing vasoconstriction

    Decongestants MOA?

  • vasodilation; vasoconstriction

    Increased __________ leads to congestion while increased __________ leads

    to decongestion.

  • phenylephrine, oxymetazoline

    What are the topical decongestants? (2)

  • Rhinitis medicamentosa

    - a rebound vasodilation that can occur that results in more severe

    congestion

  • b

    Slower onset + longer DOA

    a) topical decongestants

    b) systemic decongestants

  • a

    More prone to cause Rhinitis medicamentosa.

    a) topical decongestants

    b) systemic decongestants

  • b

    Must avoid concomitant use of MAO inhibitors when taking.

    a) topical decongestants

    b) systemic decongestants

  • e

    Which is a mast-cell stabilizer?

    a) pseudoephedrine

    b) Ipratropium Bromide

    c) phenylephrine

    d) montelukast

    e) cromolyn sodium

  • b

    Which is an anticholinergic nasal spray?

    a) pseudoephedrine

    b) Ipratropium Bromide

    c) phenylephrine

    d) montelukast

    e) cromolyn sodium

  • d

    Good in combination when a patient has asthma.

    a) pseudoephedrine

    b) Ipratropium Bromide

    c) phenylephrine

    d) montelukast

    e) cromolyn sodium

  • defensive; underlying cause

    Cough is a ________ reflex, therefore we should treat the ________.

  • c

    Which is considered a local anesthetic?

    a) Guaifenesin

    b) Dextromethorphan

    c) Benzonatate

    d) Codeine

  • c

    Which acts on respiratory stretch receptors?

    a) Guaifenesin

    b) Dextromethorphan

    c) Benzonatate

    d) Codeine

  • d

    Which is a mu-opioid receptor agonist?

    a) Guaifenesin

    b) Dextromethorphan

    c) Benzonatate

    d) Codeine

  • b

    Which increases the threshold for cough reflex?

    a) Guaifenesin

    b) Dextromethorphan

    c) Benzonatate

    d) Codeine

  • b

    Which is to be avoided when a patient is taking MAO inhibitors?

    a) Guaifenesin

    b) Dextromethorphan

    c) Benzonatate

    d) Codeine

  • CYP2D6

    Dextromethorphan is metabolized via _________.

  • a

    Which is best for productive coughs?

    a) Guaifenesin

    b) Dextromethorphan

    c) Benzonatate

    d) Codeine

  • increases the volume; reduces viscosity

    Guaifenesin __________ & ___________ of mucus.

  • Benzonatate, codeine, dextromethorphan

    What are the antitussives? (3)

  • guaifenesin

    What are the expectorants?

  • pseudoephedrine, phenylephrine

    What are the systemic decongestants? (2)

  • medullary cough center

    Codeine is an opioid that acts on the ____________.

  • b

    Which is an NMDA receptor antagonist?

    a) Guaifenesin

    b) Dextromethorphan

    c) Benzonatate

    d) Codeine