2023-12-08T04:36:22+03:00[Europe/Moscow] en true <p>HLA-DRB1 isotype </p>, <p>a</p>, <p>a</p>, <p>c</p>, <p>b</p>, <p>ESR, CRP</p>, <p>HLA-B27 isotype </p>, <p>progressive joint destruction/deformities, dactylitis, enthesitis, progression to arthritis mutilans </p>, <p>enthesitis </p>, <p>physical exam, x-ray </p>, <p>&lt;45 yo</p>, <p>&gt; 45 yo</p>, <p>SLC family 2, ATP binding cassette subfamily G</p>, <p>calcium pyrophosphate dihydrate </p> flashcards
Patho of RA, OA, and Gout

Patho of RA, OA, and Gout

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  • HLA-DRB1 isotype

    Which genetic mutation can cause RA?

  • a

    Which are auto-antibodies that precipitate when blood cools?

    a) Rheumatoid Factor (RF0

    b) Matrix Metalloprotease-1 (MMP-1)

    c) Pannus

  • a

    Which binds with IgG to form complexes that contribute to RA?

    a) Rheumatoid Factor (RF0

    b) Matrix Metalloprotease-1 (MMP-1)

    c) Pannus

  • c

    Which is a destructive vascular granulation tissue caused by

    inflammation?

    a) Rheumatoid Factor (RF0

    b) Matrix Metalloprotease-1 (MMP-1)

    c) Pannus

  • b

    Which destroys Collagen I?

    a) Rheumatoid Factor (RF0

    b) Matrix Metalloprotease-1 (MMP-1)

    c) Pannus

  • ESR, CRP

    What are acute phase reactants involved in RA? (2)

  • HLA-B27 isotype

    Which genetic mutation can cause Psoriatic Arthritis?

  • progressive joint destruction/deformities, dactylitis, enthesitis, progression to arthritis mutilans

    What are the clinical manifestations of Psoriatic Arthritis? (4)

  • enthesitis

    -inflammation of where a tendon or ligament attaches to a bone

  • physical exam, x-ray

    How is Osteoarthritis diagnosed? (2)

  • <45 yo

    When is OA more common in men?

  • > 45 yo

    When is OA more common in women?

  • SLC family 2, ATP binding cassette subfamily G

    Which genes are related to Gout? (2)

  • calcium pyrophosphate dihydrate

    Which mineral is involved in Pseudogout?