Hosam Mohamed-
a-neurotoxins, tubocurarine
What are the natural NM blockers? (2)
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b
Which binds irreversibly?
a) Tubocurarine
b) a-neurotoxin
-
b
Which causes respiratory failure, paralysis, and death?
a) Tubocurarine
b) a-neurotoxin
-
a
Which has an aromatic cationic structure?
a) Tubocurarine
b) a-neurotoxin
-
hydrolysis; cholinesterases
Succinylcholine is metabolized via ______ by _______.
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a
Which is a non-depolarizing NM blocker?
a) Tubocurarine
b) a-neurotoxin
-
4; 10
Atracurium has _____ stereogenic centers and is a mixture of ______ diastereomers.
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C17; C3
______ hydrolysis of Pancuronium produces an inactive metabolite while
______ hydrolysis produces a less active metabolite.
-
a
Which displays a morpholine ring?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
-
b
Which binds to M2 receptors?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
-
b,c
Which have BBW for experienced administration?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
-
b
Which increases heart rate and blood pressure?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
-
b
Which is used as lethal injection and euthanasia?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
-
7 negative charges; quaternary ammonium drugs
Sugammadex has _________ to bind _________.
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n-methylcarbamate; slows down AChE regeneration
What is the functional group used in AChE inhibitors? What is its function?
-
d
Which DOES NOT have a carbamate?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
-
c
Which has a dimethyl carbamate and quaternary pyridinium?
a) physostigmine
b) neostigmine
c) pyridiostigmine
d) edrophonium
-
a,c
Which have rapid onsets?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
-
d,e
Which are metabolized via rapid hydrolysis?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
