a-neurotoxins, tubocurarine
What are the natural NM blockers? (2)
b
Which binds irreversibly?
a) Tubocurarine
b) a-neurotoxin
b
Which causes respiratory failure, paralysis, and death?
a) Tubocurarine
b) a-neurotoxin
a
Which has an aromatic cationic structure?
a) Tubocurarine
b) a-neurotoxin
hydrolysis; cholinesterases
Succinylcholine is metabolized via ______ by _______.
a
Which is a non-depolarizing NM blocker?
a) Tubocurarine
b) a-neurotoxin
4; 10
Atracurium has _____ stereogenic centers and is a mixture of ______ diastereomers.
C17; C3
______ hydrolysis of Pancuronium produces an inactive metabolite while
______ hydrolysis produces a less active metabolite.
a
Which displays a morpholine ring?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
b
Which binds to M2 receptors?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
b,c
Which have BBW for experienced administration?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
b
Which increases heart rate and blood pressure?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
b
Which is used as lethal injection and euthanasia?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
7 negative charges; quaternary ammonium drugs
Sugammadex has _________ to bind _________.
n-methylcarbamate; slows down AChE regeneration
What is the functional group used in AChE inhibitors? What is its function?
d
Which DOES NOT have a carbamate?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
c
Which has a dimethyl carbamate and quaternary pyridinium?
a) physostigmine
b) neostigmine
c) pyridiostigmine
d) edrophonium
a,c
Which have rapid onsets?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium
d,e
Which are metabolized via rapid hydrolysis?
a) Rocuronium
b) Pancuronium
c) Vercuronium
d) atracurium
e) cistracurium