2023-10-21T19:21:52+03:00[Europe/Moscow] en true <p>&gt;=25 mmHg</p>, <p>schistosomiasis, congenital HD</p>, <p>SSRIs ( increase risk in newborns), weight loss drugs, amphetamines </p>, <p>family history, obesity + OSA, female gender, pregnancy, higher altitudes </p>, <p>inhaled NO, IV: epoprostenol, adenosine </p>, <p>reduction of mPAP by 10-40 mmHg</p>, <p>assess treatment interventions; follow disease progression </p>, <p>right heart catheterization </p>, <p>African-Americans, women </p>, <p>50-65 yo</p>, <p>increase; decade</p>, <p>b</p>, <p>50-70 yo</p>, <p>amiodarone, nitrofurantoin, chemo, methotrexate</p>, <p>idiopathic, drug-induced, radiation, environmental, autoimmune, occupational </p>, <p>Hypersensitivity Pneumonitis </p>, <p>Autoimmune PF</p>, <p>Pneumoconiosis (Occupational)</p>, <p>chest exam, PFT, pulse oximetry, High-resolution CT</p>, <p>subacute dyspnea, nonproductive cough, velcro crackles </p>, <p>current/former smoker, male, viral infections, GERD</p>, <p>b</p>, <p>3 years</p>, <p>respiratory failure, right-sided HF</p>, <p>smoking/2nd hand smoke, face mask</p> flashcards
Intro to Pulmonary Arterial HTN & Fibrosis

Intro to Pulmonary Arterial HTN & Fibrosis

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  • >=25 mmHg

    Pulmonary HTN is defined as ________ in the setting of normal fluid status.

  • schistosomiasis, congenital HD

    What is the most common cause of PAH worldwide? (2)

  • SSRIs ( increase risk in newborns), weight loss drugs, amphetamines

    What drugs can cause PAH? (3)

  • family history, obesity + OSA, female gender, pregnancy, higher altitudes

    What are the risk factors for PAH? (5)

  • inhaled NO, IV: epoprostenol, adenosine

    Which vasodilators are used in right heart catheterization? (3)

  • reduction of mPAP by 10-40 mmHg

    What is indicative of a positive vasoreactivity response?

  • assess treatment interventions; follow disease progression

    What is the purpose of an echocardiography? (2)

  • right heart catheterization

    What is the gold standard for Diagnosing PAH?

  • African-Americans, women

    Mortality rates of PAH are highest in who? (2)

  • 50-65 yo

    What is the mean age of diagnosis for PAH?

  • increase; decade

    There is a _______ in incidence of Pulmonary Fibrosis with each _____ of age.

  • b

    This is more common in men.

    a) PAH

    b) Pulmonary Fibrosis

  • 50-70 yo

    What is the age of diagnosis in PF?

  • amiodarone, nitrofurantoin, chemo, methotrexate

    What drugs can cause Drug-Induced PF? (4)

  • idiopathic, drug-induced, radiation, environmental, autoimmune, occupational

    What are the 6 types of PF?

  • Hypersensitivity Pneumonitis

    -exposure to mold, bacteria, animal droppings, or other triggers that cause PF

  • Autoimmune PF

    -rheumatoid arthritis; also known as connective-tissue disease related.

  • Pneumoconiosis (Occupational)

    - exposure to asbestos, coal, silica, or dust

  • chest exam, PFT, pulse oximetry, High-resolution CT

    How do we diagnose PF? (4)

  • subacute dyspnea, nonproductive cough, velcro crackles

    What are the clinical findings of a chest exam in PF? (3)

  • current/former smoker, male, viral infections, GERD

    Risk factors for PF? (4)

  • b

    Which has a worse prognosis?

    a) PAH

    b) Pulmonary Fibrosis

  • 3 years

    What is the median survival from the time of diagnosis? *PF

  • respiratory failure, right-sided HF

    What is the cause of death in PF? (2)

  • smoking/2nd hand smoke, face mask

    To lower the risk of developing PF, what should be avoided/done? (2)