2022-08-24T04:33:01+03:00[Europe/Moscow] en true <p>solution</p>, <p>parenteral solution</p>, <p>Hydrogen bond</p>, <p>Liposomes</p>, <p>Latent heat of fusion</p>, <p>solid</p>, <p>Crystalline solid</p>, <p>Amorphous </p>, <p>Eutectic mixture</p>, <p>amorphous solid</p>, <p>Cis</p>, <p>Anyhydrous</p>, <p>Anyhydrous molecule</p>, <p>Hydrate molecule </p>, <p>lower solubility</p>, <p>Trans</p>, <p>Polymorphism</p>, <p>True</p>, <p>solubility, stability, and compressibility </p>, <p>eutectic point</p>, <p>False; 3 phases</p>, <p>Eutectic Mixtures</p>, <p>cis isomers, amorphous forms, anhydrous forms, salt forms, less inter/intra molecular H-bonds, polymorphs with lower melting points, shorter c-chain length, forms with branched chain, forms with greater degree of unsaturation, eutectics, particle size</p>, <p>lower M.W.</p>, <p>Unsaturated molecule</p>, <p>vapor pressure, boiling point, surface tension, osmotic pressure</p>, <p>Equilibrium Vapor Pressure</p>, <p>volume or weight of liquid, atmospheric pressure</p>, <p>temperature </p>, <p>Boiling Point</p>, <p>Latent Heat of Vaporization</p>, <p>Cis; more polar</p>, <p>increase in chain length, decrease in number of double bonds</p>, <p>Miscibility</p>, <p>Pressure</p> flashcards
Intermolecular forces

Intermolecular forces

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  • solution

    chemically and physically homogenous mixture of two or more substances

  • parenteral solution

    for injection IV, IM, or SQ; few if any aqueous inactive; rigid standards for sterility; free of particulates; free of pyrogens; isotonic; immediate effect. (doesn't go through GI tract)

  • Hydrogen bond

    attraction of hydrogen atom for a strongly electronegative atom such as oxygen, nitrogen, fluoride and to some extent sulfur.

  • Liposomes

    a minute spherical sac of phospholipid molecules enclosing a water droplet, especially as formed artificially to carry drugs or other substances into the tissue; consists of a polar head and a hydrophobic tail

  • Latent heat of fusion

    the heat absorbed or liberated when one gram of a solid melts or freezes

  • solid

    Which state of matter has very little kinetic energy

  • Crystalline solid

    any structure of ions, molecules, or atoms that are held together in an ordered, three-dimensional arrangement.

  • Amorphous

    solid in which the atoms and molecules are not organized in a definite lattice pattern

  • Eutectic mixture

    the specific composition of at least two solid components that produces a change of phase to liquid at a certain temperature

  • amorphous solid

    Which is more soluble, crystalline or amorphous solids?

  • Cis

    Which is more soluble, cis or trans molecules?

  • Anyhydrous

    Which is more soluble, Anydrous or Hydrate molecules?

  • Anyhydrous molecule

    molecules that do not contain water

  • Hydrate molecule

    molecules that do contain water

  • lower solubility

    Higher melting point =

  • Trans

    Which isomers have higher melting points?

  • Polymorphism

    -elemental substances that exist in more than one form

    - have same molecular structure, but different:

    -crystalline forms

    -different melting points

    -X-ray diffraction patterns

    -solubility

  • True

    Many drugs exhibit polymorphism. T/F?

  • solubility, stability, and compressibility

    What are some implications of polymorphisms?

  • eutectic point

    lowest temperature at which existence of a liquid phase is possible

  • False; 3 phases

    At the eutectic point 2 phases co-exist. T/F?

  • Eutectic Mixtures

    ibuprofen, methyl nicotinate, promethazine, benzocaine, levamisole, sulfiram

  • cis isomers, amorphous forms, anhydrous forms, salt forms, less inter/intra molecular H-bonds, polymorphs with lower melting points, shorter c-chain length, forms with branched chain, forms with greater degree of unsaturation, eutectics, particle size

    What are some ways to increase solubility of solid solutes?

  • lower M.W.

    Shorter C-chain length = what?

  • Unsaturated molecule

    molecules that possess a double bond

  • vapor pressure, boiling point, surface tension, osmotic pressure

    What are some characteristics that apply to liquids?

  • Equilibrium Vapor Pressure

    pressure of saturated vapor above the liquid

  • volume or weight of liquid, atmospheric pressure

    Vapor pressure does not depend on _ & _

  • temperature

    Vapor pressure depends on __

  • Boiling Point

    temperature at which vapor pressure of a liquid equals the atmospheric pressure.

  • Latent Heat of Vaporization

    the amount of heat that is absorbed when a liquid vaporizes at the normal boiling point.

  • Cis; more polar

    Which have a higher boiling point, cis or trans? And why.

  • increase in chain length, decrease in number of double bonds

    In molecules with hydrophobic groups, boiling point increases with

  • Miscibility

    he property of two substances to mix in all proportions (that is, to fully dissolve in each other at any concentration), forming a homogeneous mixture (a solution)

  • Pressure

    Solubility in gases is dependent on what?