2023-09-03T04:05:31+03:00[Europe/Moscow] en true <p>heart block; bradycardia</p>, <p>reactive airway diseases, valvular heart disease, ED, Raynauds/ PAD</p>, <p>HFrEF/HFrpEF, stable ischemic heart disease, abdominal aortic aneurysm, arrhythmias </p>, <p>vasodilators </p>, <p>b</p>, <p>d</p>, <p>c</p>, <p>a</p>, <p>b</p>, <p>b</p>, <p>f; lipophilic </p>, <p>exhibit partial agonist activity at rest, no decrease in resting HR, good for sinus bradycardia; doesn't improve CV risk</p>, <p>anti-arrhythmic properties, QTc prolongation/ seizures, no clinical advantage in HTN</p>, <p>mask; sweating </p>, <p>clonidine, dilitazem, verapamil, amiodarone, NSAIDS</p>, <p>increased rebound HTN w/ clonidine withdrawal </p>, <p>heart block, AV block, bradycardia</p>, <p>reduced efficacy </p>, <p>atenolol, nadolol </p>, <p>cocaine; stimulates a &amp; b receptors; unopposed stimulation of a receptors increases PR, HR, BP</p>, <p>metoprolol, propranolol, carvedilol, labetalol </p>, <p>upregulation &amp; hypersensitivity of B-receptors</p>, <p>increased BP/HR, sweating, malaise </p>, <p>f; may have to restart BB</p>, <p>propranolol, metoprolol, carvediolol</p>, <p>hydrophilic </p>, <p>b</p>, <p>food; CR/XL/LA</p> flashcards
HTN-Beta Blockers

HTN-Beta Blockers

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  • heart block; bradycardia

    BBs are CI in what conditions? (2)

  • reactive airway diseases, valvular heart disease, ED, Raynauds/ PAD

    What conditions should we avoid BBs in? (4)

  • HFrEF/HFrpEF, stable ischemic heart disease, abdominal aortic aneurysm, arrhythmias

    Compelling indications of BBs? (4)

  • vasodilators

    Giving BBs with ______ can manage reflex tachycardia.

  • b

    BBs & ________ can cause heart block.

    a) ARBS

    b) CCBs

    c) ACEis

    d) A2-agonists

  • d

    BBs & ________ can cause bradycardia.

    a) ARBS

    b) CCBs

    c) ACEis

    d) A2-agonists

  • c

    Useful in managing tremors and migraines.

    a) mixed A & B- blockers

    b) B1-selective

    c) Nonselective B-Blockers

    d) B1-selective + NO production

  • a

    These possess the greatest risk of orthostasis.

    a) mixed A & B- blockers

    b) B1-selective

    c) Nonselective B-Blockers

    d) B1-selective + NO production

  • b

    Mainly for reducing HR.

    a) mixed A & B- blockers

    b) B1-selective

    c) Nonselective B-Blockers

    d) B1-selective + NO production

  • b

    Best for patients with reactive airway disease & diabetes

    a) mixed A & B- blockers

    b) B1-selective

    c) Nonselective B-Blockers

    d) B1-selective + NO production

  • f; lipophilic

    Highly hydrophilic BBs tend to be the best for

    tremors, thyroid, and migraines. T/f?

  • exhibit partial agonist activity at rest, no decrease in resting HR, good for sinus bradycardia; doesn't improve CV risk

    What are the characteristics of drugs with Intrinsic Sympathomimetic Activity (ISA) *3

  • anti-arrhythmic properties, QTc prolongation/ seizures, no clinical advantage in HTN

    What are the characteristics of drugs with Membrane Stabilizing Activity? (MSA) *3

  • mask; sweating

    Beta-blockers can _____ the symptoms of hypoglycemia except ______.

  • clonidine, dilitazem, verapamil, amiodarone, NSAIDS

    Which drugs should we avoid with BBs? (5)

  • increased rebound HTN w/ clonidine withdrawal

    BBs + clonidine = (3)

  • heart block, AV block, bradycardia

    BBs + CCB's = (3)

  • reduced efficacy

    BBs + NSAIDS =

  • atenolol, nadolol

    Which BBs are cleared renally? (2)

  • cocaine; stimulates a & b receptors; unopposed stimulation of a receptors increases PR, HR, BP

    Which narcotic should especially be avoided when using BBs?

  • metoprolol, propranolol, carvedilol, labetalol

    Which BBs are NOT once daily? (4)

  • upregulation & hypersensitivity of B-receptors

    What is the mechanism behind BB withdrawal?

  • increased BP/HR, sweating, malaise

    Symptoms of BB withdrawal? (3)

  • f; may have to restart BB

    If symptoms present while tapering off, you should proceed with quitting. T/F?

  • propranolol, metoprolol, carvediolol

    What are the Lipophilic Beta blockers? (3)

  • hydrophilic

    __________ beta blockers are best for reducing sedation & dream SE's.

  • b

    Which CR/XL/LA formulation can be split?

    a) labetalol

    b) metoprolol

    c) carvedilol

    d) propranolol

  • food; CR/XL/LA

    ________ helps smooth out the absorption of ________ products.