The coronary arteries fill with blood when the ventricles relax, not when they contract This is because when the ventricles contract, they create high pressure in the aorta, which is where the
coronary arteries originate This pressure compresses the openings of the coronary arteries and
reduces blood flow to the heart muscle 1 2. When the ventricles relax, the pressure in the aorta drops and the coronary arteries expand, allowing blood to flow into them. The coronary blood flow is also regulated by other factors, such as oxygen demand, metabolic activity, and autonomic nervous system.