Integumentary System
Skin is an organ; integumentary system includes skin and its derivates
Derivates = hair, nails, glands, scales, feathers, furs, hooves, antlers
Functions of Integumentary System
Body temp reg., Vasomotor Control, Protection, Perception, Excretion/Secretion
Body Temp Regulation
1. Sweating
2. Vasomotor Control: control blood vessels
Hot = dilate vessels
Cold = constrict vessels
Brain prioritizes main organs over extremities
Protection function
skin is 1st line of defense against microorganisms.
They invade when abrasion, laceration, break etc.
the pH of skin is not conducive to growth of microorganisms = 5ish
Perception function
feeling, tactile/texture/temp feedback
Excretion/Secretion Function
Excretion - leaves body (sweat, oil)
Secretion - releases something but does not leave body
ex of secretion = tanning, pigment melena is released but stays inside body darkening skin
Synthesis of integumentary system
Glands:
Sweat glands
Oil glands
Mammary glands
Skin composition
Epidermis
Dermis
Hypodermis
Types of Skin
Thin - epidermis has 4 layers; has hair
Thick - epidermis has 5 layers; lacks hair
Layers of Epidermis
5 layers; called epidermal layers
CLGSB
1. Stratum Corenum (extremely thick)
2. Stratum Lucidum (layer missing in thin layer, very thin)
3. Stratum Granulosum (very thin)
4. Stratum Spinosum (very thick)
5. Stratum Basale (very thin)
Stratum Basale
Mitotically active; parent cell divides produces 2 daughter cells in basement membrane and migrate towards surface; takes 10-14 days for new skin cell to reach top
Keratinocytes
produces keratin; as cells migrate towards the surface, keratin kills new skin cells and are dead on surface, as they move up they get thinner due to force
Melanocytes
produce melanin (hormone);
melanin is dark/light aspect of skin
unicellular endocrine glands make melanin
Tactile/Merkel Cells
receptors for perception; temp/texture/pressure
Skin Tone Composition
Melanin- dark/light
Ceratines - yellow/orange pigments
Hemoglobin (Fe-) - pinkish pigments
Non-pigmented granular dendrocytes
phagocytes; devour material on skin; doesn't discern what is being phagocytized
Top Dermis Region
Top (20-35%)
1. Papillary region-loose CT and elastic CT
2. Dermal papillae - belong to dermis-stick up
3. Epidermal pegs - belongs to epidermis-stick down
Interlocking fingers of papillae and pegs allow skin to stretch.
Stretch marks caused by tears in collagen fibers.
Bottom Dermis Region
Lower (65-80%)
1. Reticular region -dense irregular CT, collagen, and elastic CT
2. Adipocytes
3. Hair follicles and associated structures (hair shaft, foot, arrector pili muscle -piloerection, hair stands up)
Widespread pillow erection
Muscle contracts, hair stands up
Arrector pili muscle contracts, hair stands up = goosebumps
Animals have ability to make hair stand up for warmth.
air is insulator to stay warm.
Oil (sebaceous glands)
deposit oil into hair follicle.
exact purpose not known, moisturizes hair to prevent hair splitting
Sweat Glands (sudoriferous)
Eccrine (merocrine, simple coiled tubular) - produce a classic watery type of sweat, for cooling off, open on the surface, present at birth.
Apocrine (simple coiled tubular) - produce oily kind of sweat and is associated with odor/smell; open into a hair follicle. Develop at puberty.
Phermones
detected by other people (olfactory sense) may be conscious/unconscious
ex: menstrual cycles syncing up, infants nursing, dogs marking
Pacinian corpuscles
deep pressure receptors
receptors range from fine to deep touch
Subcutaneous Layer or Hypodermis Composition
1. Loose CT and adipose CT
2. Pacinian corpuscles
3. Sudoriferous glands
Sebaceous (oil) gland
holocrine, simple branched -> sebum (oil)
Sudoriferous (sweat) gland
1. Eccrine: merocrine, simple coiled tubular -> sweat (cooling)
2. Apocrine, simple coiled tubular -> sweat (odor/pheromones)
Mammary (milk) gland
merocrine and apocrine, compound tubular -> milk
Ceruminous gland
produces ear wax
water/insect repellent
Substances produced by skin
1. Milk
2. Eccrine sweat
3. Apocrine sweat
4. Sebum
5. Cerumen
6. Vitamin D (needs sun)
7. Keratin
8. Melanin
Functions of Skeletal system
1. Movement - muscles pull on bones
2. Support
3. Storage - Ca+, Triglycerides (fats)
4. Production- hemopoiesis: blood made in bone marrow
5. Protection - WBC/Immunity, physical production
Long Bones
may not be actually lone, but are referenced as long bones because of specific features (humerus)
Flat Bones
may not actually be flat but are referenced as flat because of specific features (ribs, clavicle, sternum)
Cortex: compact bone
Dipole: spongy bone
Sesamoid Bones
bones that develop in a tendon (patella)
1. Patellar tendon ligament: the tendon that runs across your knee from your femur to your tibia
Short Bones
carpals and tarsals
Irregular Bones
vertebrae, sphenoid
Sutural Bones
very often located in the lambdoidal and occipital sutures
Long Bone Anatomy
2 ends and a shaft
1. each end is called an epiphysis
2. the shaft is called a diaphysis
2 types of bone material
1. Compact Bone - superficial
2. Medullary cavity(deep) - yellow bone fills it fat
Hyaline cartilage on articulating surfaces (ends)
Lining Bone is periosteum
1. allows bone to increase in diameter
2. strengthens bones
3. appears shiny
Joints
head + fossa = joints
1. head - large round smooth protrusion
2. fossa - depression that the head sits in
shoulder joint
head of Humerus + glenoid fossa
hip joint
head of femur + acetabulum
proximal radioulnar joint
head of radius + radial notches of ulna
Condyle + fossa or facet
Joint
Facet: shallow fossa
Condyle: Small head
temporomandibular joint
mandibular condyles + condylar fossa of temporal fossa
atlantooccipital joint
occipital condyles + superior articular surfaces (facets) of atlas (c1)
Atlantoaxial joint
dens of axis (C2) + fovea dentis of atlas (c1)
Non-articular surfaces
myo attachments - tubercles; trochanter; tuberosity
Myo attachments
muscles connected to bones via tendons
tubercles
ex: greater/lesser of humerus
slightly raised surfaces
trochanter
large irregular meat hooks
ex: femur (greater and lesser)
tuberosity
ex: ischial tubersoity
rough slightly raised surfaces
Myo origin
attachment that moves the least
Myo insertion
attachment that moves the most; moves towards the origin
Process
any bone marking or surface features
1. a part of a bone that articulates (doesn't move) with another bone
Depressions and Openings
Foramen - hole
Fissure - slit
Canal - tunnel
a meatus is the same as a canal: a significant horizontal distance is traversed
Roof: Cribriform plate of ethmoid
Floor: Hard palate
Bridge: Nasal bones
Lateral Framework: Frontal process of maxilla
7 Bones that Contribute to Orbital Fossa
Fmolesz
1. frontal bone
2. ethmoid bone
3. lacrimal bone
4. maxilla
5. zygomatic
6. sphenoid
7. orbital plate of palatine bone
Bone Development
1. Osteogenesis = sperm+egg -> I-cell embryo or zygote
2. embryo differentiates -> hyaline cartilage or fibrous membrane
Endochondral Ossification (until grown)
Hyaline cartilage -> Long Spongy/compact bone
Intramembranous Ossification (until you die)
Fibrous membrane -> Flat spongy/compact bones
intramembranous ossification
fibrous membranes
(starts during embryo gensis)
Membrane is being replaced by bone.
At birth ossification is not complete to pass birth canal and brain grows faster than the skull.
endochondral ossification
hyaline cartilage
(starts during embryo gensis)
1. Blood vessels grow through the perichondrium, in the diaphysis.
2. Blood brings calcium into the cartilage, this becomes primary ossification center. Cartilage cells swell and burst -> change in pH.
3. Repeat steps 1-2 in each epiphysis.
4. Ossification spreads from each epiphysis toward the diaphysis and from the diaphysis toward the epiphysis.
5. When growth is complete the epiphyseal plate ossifies and becomes the epiphyseal line.
Vertebral Disorders
All vertebral disorders are associated with Calcium or Vitamin D deficiency.
Lordosis (lumbar)
lumbar curvature is exaggerated; associated with obesity; gestational (temporary) lordosis related to pregnancy
Kyphosis (thoracic)
part of aging; compress more on anterior side than posterior side, bends us over "hunch back"
Scoliosis
lateral misalignment of spine; can be born with it; can interfere with breathing
Spina Bifida
bifurcated/forked spinous process.
Lamina don't fuse. Variable expression.
Can cause quadriplegia, depth of spina bifida; too little folic acid; too much retinoic acid (Vit. A)
Exencephaly
brain is outside cranial vault/skull
Anencephaly
absence of brain; incomplete brain
Exencephaly/anencephaly often occur together
Osteoporosis
condition which bones become weak and brittle.
stress/pathological fractures due to hormone levels/cortisol abuse
osteomalacia (ricketts)
soft bones; Vit D deficiency; bowed legs
Undernourished
not enough calories to sustain life
Malnourished
Lacking essential vitamins/minerals
Osteomyelitis
infection of red bone marrow
inflammation or swelling occurs in the bone
polydactyl
many digits (autosomal dominant)
oligodactyl
few digits (autosomal dominant)
syndactyl
fused/webbed digits (autosomal dominant)
Phocomelia
lack of proximal bone(s); no Humerus/femur
Micromelia
all bones are present, but short
Nasal Septum Joint
Vomer Bone + Perpendicular plate of ethmoid bone
Stylohyoid Ligament Joint
Styloid Process + Lesser horns of hyoid bone
Zygomatic Arch Joint
zygomatic process of temporal bone + temporal process of zygomatic bone
Hard Palate or Roof of oral cavity Joint
horizontal plates of palatine bone + palatine process of maxilla
Atlantooccipital Joint (Yes)
Occipital condyles + superior articular surfaces (facets) of the atlas (C1)
Atlantoaxial joint (No)
Dens or Odontoid Process of Axis (C2) + Anterior articular surface of the atlas (facet) or Fovea Dentis (c1)
Vertebrovertebral Joint (spine or vertebral column)
Superior articular process of underlying vertebra + inferior articular process of overlying vertebra
Costovertebral joints
Head of ribs tubercle of ribs + body of vertebrae (facets or demi-facets) + transverse process of vertebrae
Sternocostal joint (hyaline cartilage)
sternal end of rib + cartilage of sternum
Sternoclavicular Joint
Medial aspect of clavicle + manubrium of sternum
Acromioclavicular joint
lateral aspect of clavicle + acromion process of scapula
Shoulder joint (glenohumeral)
glenoid fossa + head of humerus
Humeroulnar joint (hinge action of elbow anteriorly)
coronoid process of ulna + coronoid fossa of humerus
Humeroulnar (hinge action of elbow posteriorly)
olecranon process of ulna + olecranon fossa of humerus
Humeroulnar (hinge action of elbow medially)
Medial condyle or trochlea of Humerus + trochlear notch of ulna
Humeroradial Joint - rotation of lower arm
Lateral condyle or capitulum of Humerus + head or capitate of radius
Radioulnar Joint - rotation of lower arm
Radial notch of ulna + head of radius
Carpometacarpal joints
distal ends of each carpal + proximal bones of of the metacarpals
Metacarpophalangeal Joint
distal heads of metacarpals + proximal phalanges of each digit
Interphalangeal Joint
(proximal or distal phalangeal joints occur in all fingers and toes except hallux and pollex)
phalange + phalange
Saddle Joint
First metacarpal + Trapezium of the carpals
Sacroiliac joint
(only articulation between the lower appendicular skeleton and axial skeleton)
ilium + sacrum
(posterior superior iliac spine, posterior inferior iliac spine) + sacrum
Hip Joint
Acetabulum + head of femur
Symphysis Pubis Joint
(fibrocartilaginous joint)
pubis crest of left os coxae + pubis crest of right os coxae