Hosam Mohamed-
enoxaparin, dalteparin
What are our Low MW Heparins? (2)
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-ban suffix + fondaparinux
What are our Factor Xa inhibitors?
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dabigatran/ pradaxa
What is our direct thrombin inhibitor?
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warfarin
What is our Vitamin K antagonist?
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alteplase, tenecteplase, reteplase, streptokinase
What are our thrombolytics? (4)
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1 mg/kg SQ BID; renal dose 1mg/kg sq o.d.
Explain Enoxaparin Venous ThromboEmbolism dosing.
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200 IU/kg o.d.
Explain Dalteparin VTE dosing.
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parental overlap for 5 days + 150 mg po BID
Explain Dabigatran VTE dosing.
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15 mg po BID x 21 days; 20 mg po o.d.; may lower to 10 mg po o.d.; no parenteral overlap
Explain Rivaroxaban VTE dosing.
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10 mg po BID x 7 days; 5 mg po BID; may lower to 2.5 mg po BID after 6 months; no parenteral overlap
Explain Apixaban VTE dosing.
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Parenteral overlap for 5 days + 60 mg daily
Explain Edoxaban VTE dosing.
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d
Which has no dose adjustments?
a) dabigatran
b) rivaroxaban
c) apixaban
d) edoxaban
e) enoxaparin
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a, d
Which has parenteral overlap?
a) dabigatran
b) rivaroxaban
c) apixaban
d) edoxaban
e) enoxaparin
