enoxaparin, dalteparin
What are our Low MW Heparins? (2)
-ban suffix + fondaparinux
What are our Factor Xa inhibitors?
dabigatran/ pradaxa
What is our direct thrombin inhibitor?
warfarin
What is our Vitamin K antagonist?
alteplase, tenecteplase, reteplase, streptokinase
What are our thrombolytics? (4)
1 mg/kg SQ BID; renal dose 1mg/kg sq o.d.
Explain Enoxaparin Venous ThromboEmbolism dosing.
200 IU/kg o.d.
Explain Dalteparin VTE dosing.
parental overlap for 5 days + 150 mg po BID
Explain Dabigatran VTE dosing.
15 mg po BID x 21 days; 20 mg po o.d.; may lower to 10 mg po o.d.; no parenteral overlap
Explain Rivaroxaban VTE dosing.
10 mg po BID x 7 days; 5 mg po BID; may lower to 2.5 mg po BID after 6 months; no parenteral overlap
Explain Apixaban VTE dosing.
Parenteral overlap for 5 days + 60 mg daily
Explain Edoxaban VTE dosing.
d
Which has no dose adjustments?
a) dabigatran
b) rivaroxaban
c) apixaban
d) edoxaban
e) enoxaparin
a, d
Which has parenteral overlap?
a) dabigatran
b) rivaroxaban
c) apixaban
d) edoxaban
e) enoxaparin