2023-09-20T23:46:40+03:00[Europe/Moscow] en true <p>block voltage sensitive, L-type calcium channels in SA &amp; AV nodes; slowing conduction and reducing contractility </p>, <p>Verapamil; diltiazem </p>, <p>atrial; av node </p>, <p>f; can cause arrhythmias </p>, <p>hypotension, sinus bradycardia/av block, constipation </p>, <p>inhibits Na+/K+ pump to increase concentration of intracellular calcium; increases parasympathetic outflow at SA &amp; AV node</p>, <p>agonizes adenosine receptors; activating rectifier potassium currents and causing hyperpolarization; also blocks calcium current</p>, <p>d</p>, <p>reentry pathways</p>, <p>a</p> flashcards
Class IV & Others Pharmacology (Specific)

Class IV & Others Pharmacology (Specific)

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  • block voltage sensitive, L-type calcium channels in SA & AV nodes; slowing conduction and reducing contractility

    MOA of Class IV?

  • Verapamil; diltiazem

    Which drugs are involved in this class? (2)

  • atrial; av node

    These drugs are more useful for ________ arrhythmias. Due to reentry arrhythmias requiring the _________ for conduction.

  • f; can cause arrhythmias

    Dihydropyridines are an acceptable medication class to use in arrhythmias. T/F?

  • hypotension, sinus bradycardia/av block, constipation

    AE's of Non-DHPs?

  • inhibits Na+/K+ pump to increase concentration of intracellular calcium; increases parasympathetic outflow at SA & AV node

    Digoxin MOA?

  • agonizes adenosine receptors; activating rectifier potassium currents and causing hyperpolarization; also blocks calcium current

    Adenosine MOA?

  • d

    Which has a half-life of < 10 seconds?

    a) Verapamil

    b) Dilitazem

    c) Digoxin

    d) Adenosine

  • reentry pathways

    Adenosine can interrupt ___________ through the AV node.

  • a

    Which can cause constipation when taken orally?

    a) Verapamil

    b) Dilitazem

    c) Digoxin

    d) Adenosine