block voltage sensitive, L-type calcium channels in SA & AV nodes; slowing conduction and reducing contractility
MOA of Class IV?
Verapamil; diltiazem
Which drugs are involved in this class? (2)
atrial; av node
These drugs are more useful for ________ arrhythmias. Due to reentry arrhythmias requiring the _________ for conduction.
f; can cause arrhythmias
Dihydropyridines are an acceptable medication class to use in arrhythmias. T/F?
hypotension, sinus bradycardia/av block, constipation
AE's of Non-DHPs?
inhibits Na+/K+ pump to increase concentration of intracellular calcium; increases parasympathetic outflow at SA & AV node
Digoxin MOA?
agonizes adenosine receptors; activating rectifier potassium currents and causing hyperpolarization; also blocks calcium current
Adenosine MOA?
d
Which has a half-life of < 10 seconds?
a) Verapamil
b) Dilitazem
c) Digoxin
d) Adenosine
reentry pathways
Adenosine can interrupt ___________ through the AV node.
a
Which can cause constipation when taken orally?
a) Verapamil
b) Dilitazem
c) Digoxin
d) Adenosine