2023-02-07T06:33:20+03:00[Europe/Moscow] en true <p>True</p>, <p>cepham has less ring strain</p>, <p>Ampicillin; Gm + &amp; Gm -</p>, <p>less</p>, <p>allergic</p>, <p>Penicillin </p>, <p>Gm+</p>, <p>moderate like ampicillin/amoxicillin</p>, <p>1st gen</p>, <p>a</p>, <p>b</p>, <p>c,d,e</p>, <p>a</p>, <p>c,d,e </p>, <p>c</p>, <p>a</p>, <p>b</p>, <p>cephalexin, cefadroxil, cefazolin</p>, <p>cefazolin</p>, <p>1st gen; cefaclor (2nd gen)</p>, <p>4th gen</p>, <p>3rd gen; cefuroxime (2nd gen) </p> flashcards
Cephalosporins (General)

Cephalosporins (General)

  • True

    Cephalosporin C (natural product) is not used clinically. T/F?

  • cepham has less ring strain

    What is the difference between the penam nucleus & the cepham nucleus?

  • Ampicillin; Gm + & Gm -

    Cephalosporin has a similar spectrum to what penicillin? What is the spectrum?

  • less

    Cephalosporin is ___ potent to organisms that are susceptible in both classes.

  • allergic

    Cephalosporin has far fewer ________ reactions.

  • Penicillin

    What is more active on penicillinases? Cephalosporin or Penicillin?

  • Gm+

    What kind of Pen'ase strains does cephalosporin act on?

  • moderate like ampicillin/amoxicillin

    What is the spectrum for 1st gen Cephalosporins?

  • 1st gen

    Which generation has the best activity against Gm+?

  • a

    Which generation is susceptible to cephalosporinases?

    a) 1st gen

    b) 2nd gen

    c) 3rd gen

    d) 4th gen

    e) 5th gen

  • b

    Which generation is stable/resistant to penicillinases and some cephalosporinases?

    a) 1st gen

    b) 2nd gen

    c) 3rd gen

    d) 4th gen

    e) 5th gen

  • c,d,e

    Which generation is stable/resistant to penicillinases and many cephalosporins?

    a) 1st gen

    b) 2nd gen

    c) 3rd gen

    d) 4th gen

    e) 5th gen

  • a

    Which generation has a short half-life and requires frequent dosing?

    a) 1st gen

    b) 2nd gen

    c) 3rd gen

    d) 4th gen

    e) 5th gen

  • c,d,e

    Which generations are active against Pseudomonas & Enterobacteriaceae?

    a) 1st gen

    b) 2nd gen

    c) 3rd gen

    d) 4th gen

    e) 5th gen

  • c

    What is an example of a narrow-spectrum antibiotic?

    a) gm + and some gm-

    b) gm + and many gm-

    c) gm+ only

  • a

    What is an example of an extended-spectrum antibiotic?

    a) gm + and some gm-

    b) gm + and many gm-

    c) gm+ only

  • b

    What is an example of a broad-spectrum antibiotic?

    a) gm + and some gm-

    b) gm + and many gm-

    c) gm+ only

  • cephalexin, cefadroxil, cefazolin

    What are our first generation cephalosporins?

  • cefazolin

    Which first-gen cephalosporin is used parenterally or iv/im?

  • 1st gen; cefaclor (2nd gen)

    A cephalosporin with its first four letters "cefa" is what gen? Exception?

  • 4th gen

    A cephalosporin that ends in pime is what gen?

  • 3rd gen; cefuroxime (2nd gen)

    A cephalosporin that ends in one, me, or ten is what gen? Exception?