2023-08-23T04:30:18+03:00[Europe/Moscow] en true <p>macrolides, tetracyclines, linezolid, tedizolid, clindamycin, lefamulin</p>, <p>aminoglycosides, tetracyclines</p>, <p>Synercid, erythromycin/macrolides, lincosamides, linezolid, lefamulin, aminoglycosides</p>, <p>efflux pump, porin channel deletion, beta-lactamase, binding site mutation</p>, <p>E. faecalis, anaerobes, MRSA, P. aeruginosa</p>, <p>carbapenem, 1st &amp; 2ng gen ceph, BLICs</p>, <p>vancomycin</p>, <p>MRSA, E.faecalis, Anaerobes (+)</p>, <p>doxycycline, tigecycline, omadacycline, minocycline, tetracycline, eravacycline </p>, <p>MRSA, Enterococcus </p>, <p>clindamycin </p>, <p>polymyxin, aminoglycoside, aztreonam, fosfomycin, zosyn, ceftazidime, cefepime, ceftolozane, carbapenem, fq's, nitrofurantoin</p>, <p>-floxacin suffix </p>, <p>daptomycin</p>, <p>-vancin suffix </p>, <p>bactrim; sulfamethoxazole + trimethoprim</p>, <p>metrondiazole </p>, <p>aztreonam</p>, <p>lefamulin</p>, <p>ceftaroline, vancomycin, tetracyclines, daptomycin, lipoglycopeptides, delafloxacin, clindamycin, bactrim, linezolid, fosfomycin, lefamulin</p>, <p>GI, bones, skin, lungs</p>, <p>MRSA, Enterococcus</p>, <p>everywhere except CNS &amp; lungs</p>, <p>RT, eyes, ears, nose, GI</p>, <p>atypicals</p>, <p>MRSA, VR-Entero</p>, <p>everywhere except CNS</p>, <p>bladder only</p>, <p>bladder + prostate</p>, <p>lungs + genitals </p>, <p>Moxifloxacin </p>, <p>ciprofloxacin, delafloxacin, levofloxacin </p>, <p>delafloxacin </p>, <p>MRSA, VR-entero</p>, <p>MRSA, anaerobes (+)</p>, <p>GI, skin, bones, lungs</p>, <p>MRSA</p>, <p>d</p>, <p>Pseudomonas </p>, <p>enterococcus, pseudomonas </p>, <p>MRSA, VR-entero, pseudomonas</p>, <p>MRSA, atypicals </p>, <p>Pseudomonas </p>, <p>Lungs, GI, Urine (not moxi), CNS, blood</p> flashcards
Antibiotics Class information

Antibiotics Class information

  • macrolides, tetracyclines, linezolid, tedizolid, clindamycin, lefamulin

    What are our static agents? (6)

  • aminoglycosides, tetracyclines

    Which agents act at the 30s subunit? (2)

  • Synercid, erythromycin/macrolides, lincosamides, linezolid, lefamulin, aminoglycosides

    Which agents act at the 50s subunit? (6)

  • efflux pump, porin channel deletion, beta-lactamase, binding site mutation

    What are the mechanisms of bacterial resistance (4)?

  • E. faecalis, anaerobes, MRSA, P. aeruginosa

    Which bacteria are our Beta-Lactam AB active against? (4)

  • carbapenem, 1st & 2ng gen ceph, BLICs

    Which beta-lactams cannot cross into the CNS? (3)

  • vancomycin

    What is our Glycopeptide?

  • MRSA, E.faecalis, Anaerobes (+)

    Which bacteria is Vancomycin active against? (3)

  • doxycycline, tigecycline, omadacycline, minocycline, tetracycline, eravacycline

    What are our tetracyclines? (6)

  • MRSA, Enterococcus

    Which bacteria are tetracyclines active against? (2)

  • clindamycin

    What is our lincosamide?

  • polymyxin, aminoglycoside, aztreonam, fosfomycin, zosyn, ceftazidime, cefepime, ceftolozane, carbapenem, fq's, nitrofurantoin

    What agents cover Pseudomonas? (11)

  • -floxacin suffix

    What are the FQ's?

  • daptomycin

    What is our lipopeptide?

  • -vancin suffix

    What are our lipoglycopeptides?

  • bactrim; sulfamethoxazole + trimethoprim

    What is our folate antagonist? What drugs make this up?

  • metrondiazole

    What is our nitroimidazole?

  • aztreonam

    What is our Monobactam?

  • lefamulin

    What is our pleuromutilin?

  • ceftaroline, vancomycin, tetracyclines, daptomycin, lipoglycopeptides, delafloxacin, clindamycin, bactrim, linezolid, fosfomycin, lefamulin

    Which drugs cover MRSA? (11)

  • GI, bones, skin, lungs

    Where are Tetracyclines active in the body? (4)

  • MRSA, Enterococcus

    Which bacteria are Tetracyclines active against? (2)

  • everywhere except CNS & lungs

    Where is Daptomycin active in the body?

  • RT, eyes, ears, nose, GI

    Where are macrolides active in the body? (5)

  • atypicals

    Which bacteria are Macrolides active against?

  • MRSA, VR-Entero

    Which bacteria are Lipoglycopeptides active against? (2)

  • everywhere except CNS

    Where are Aminoglycosides active in the body?

  • bladder only

    Where is nitrofurantoin active in the body?

  • bladder + prostate

    Where is Fosfomycin active in the body? (2)

  • lungs + genitals

    Where is Lefamulin active in the body? (2)

  • Moxifloxacin

    Which Fluoroquinolones are active against anaerobes?

  • ciprofloxacin, delafloxacin, levofloxacin

    Which Fluoroquinolones are active against Pseudomonas? (3)

  • delafloxacin

    Which Fluoroquinolones are active against MRSA?

  • MRSA, VR-entero

    Which bacteria are Oxazolidinones active against? (2)

  • MRSA, anaerobes (+)

    Which bacteria are Lincosamides active against? (2)

  • GI, skin, bones, lungs

    Where is Clindamycin active in the body? (4)

  • MRSA

    What is Bactrim active against?

  • d

    Polymyxin B does not make into what organ?

    a) brain

    b) GI

    c) blood

    d) kidneys

  • Pseudomonas

    Polymyxin B is active against?

  • enterococcus, pseudomonas

    Nitrofurantoin is active against what? (2)

  • MRSA, VR-entero, pseudomonas

    Fosfomycin is active against what? (3)

  • MRSA, atypicals

    Lefamulin is active against? (2)

  • Pseudomonas

    What is Monobactam used for?

  • Lungs, GI, Urine (not moxi), CNS, blood

    Where do FQ's act? (5)