2023-08-22T04:44:39+03:00[Europe/Moscow] en true <p>inhibits neuraminidase from cleaving the receptor on host cell; preventing the budding of the virus, altering aggregation and release</p>, <p>5 days</p>, <p>10 days </p>, <p>-amivir suffix</p>, <p>N&amp;V, neuropsychiatric events, abdominal pain </p>, <p>b,d</p>, <p>a</p>, <p>b</p>, <p>c</p>, <p>a</p>, <p>c</p>, <p>c,d</p>, <p>d</p>, <p>inhibits endonuclease of a selective polymerase acidic protein required for gene transcription inhibiting replication</p>, <p>d</p>, <p>d</p>, <p>d</p>, <p>UGT1A3, CYP3A4 </p>, <p>d</p> flashcards
Anti-influenza drugs

Anti-influenza drugs

Customize
collection saved
Share
Long Term Learning Spaced Repetition
Add to Long Term Learning Desk
Fast learning Repeat this set of flashcards
Preview Test Spell
Play
Match
Review

  • inhibits neuraminidase from cleaving the receptor on host cell; preventing the budding of the virus, altering aggregation and release

    What is the MOA of neuraminidase inhibitors?

  • 5 days

    How long does neuraminidase treatment last?

  • 10 days

    How long does neuraminidase prophylaxis last?

  • -amivir suffix

    How can we tell our Neuraminidase inhibitors apart?

  • N&V, neuropsychiatric events, abdominal pain

    What are the general AE's associated with Neuraminidase inhibitors? (3)

  • b,d

    Which is predominately metabolized in the liver?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • a

    Which is absorbed via inhalation?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • b

    Which has dose adjustments for renal impairment?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • c

    Which is excreted 90% unchanged in the urine?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • a

    Which causes bronchospasms, throat pain, and cough?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • c

    Which can cause increased serum glucose?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • c,d

    Which can cause hypersensitivity and skin reactions?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • d

    Which is only approved for a single dose?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • inhibits endonuclease of a selective polymerase acidic protein required for gene transcription inhibiting replication

    What is the MOA of Baloxavir Marboxil (Xofluza)?

  • d

    Which has activity against strains resistant to neuraminidase inhibitors?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • d

    Which is ONLY indicated for treatment?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • d

    Which is a prodrug?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)

  • UGT1A3, CYP3A4

    What are the CYPs responsible for metabolizing Baloxavir?

  • d

    Which can cause swollen tongue?

    a) Zanamivir

    b) Oseltamivir

    c) Peramivir

    d) Baloxavir Marboxil (Xofluza)