2023-08-23T02:11:05+03:00[Europe/Moscow] en true <p>acyclovir, valacyclovir, famciclovir</p>, <p>acyclovir, valacyclovir </p>, <p>Famciclovir </p>, <p>b </p>, <p>a,c</p>, <p>b</p>, <p>b</p>, <p>a</p>, <p>a</p>, <p>ganciclovir, valganciclovir, foscarnet, cidofovir </p>, <p>c</p>, <p>a,d </p>, <p>a,d</p>, <p>a,c,d</p>, <p>d</p>, <p>d</p>, <p>d</p>, <p>a</p>, <p>a, c, d</p>, <p>b</p>, <p>b, c </p>, <p>b</p>, <p>b</p>, <p>b</p>, <p>c</p>, <p>c</p>, <p>Ganciclovir, valganciclovir</p>, <p>Foscarnet </p>, <p>Cidofovir </p>, <p>c</p>, <p>c</p>, <p>virostatic </p> flashcards
Anti-Herpes & Anti- CMV

Anti-Herpes & Anti- CMV

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  • acyclovir, valacyclovir, famciclovir

    What drugs are used against Herpes? (3)

  • acyclovir, valacyclovir

    Which drug inhibits DNA elongation in the DNA polymerase through activity as a guanosine analog? (2)

  • Famciclovir

    Which drug inhibits DNA synthesis and replication via HSV-2 polymerase?

  • b

    Which uses IBW for dosing?

    a) valacyclovir

    b) acyclovir

    c) Famciclovir

    d) ganciclovir

  • a,c

    Which is taken 2-3 times per day?

    a) valacyclovir

    b) acyclovir

    c) Famciclovir

    d) ganciclovir

  • b

    Which is taken up to 5 days?

    a) valacyclovir

    b) acyclovir

    c) Famciclovir

    d) ganciclovir

  • b

    Which can cause acute renal failure?

    a) valacyclovir

    b) acyclovir

    c) Famciclovir

    d) ganciclovir

  • a

    Which can cause depression?

    a) valacyclovir

    b) acyclovir

    c) Famciclovir

    d) ganciclovir

  • a

    Which can cause arthralgia?

    a) valacyclovir

    b) acyclovir

    c) Famciclovir

    d) ganciclovir

  • ganciclovir, valganciclovir, foscarnet, cidofovir

    What are the anti-CMV drugs? (4)

  • c

    Which is a prodrug?

    a) valacyclovir

    b) acyclovir

    c) Famciclovir

    d) ganciclovir

  • a,d

    Which drugs have a BBW for thrombocytopenia, granulocytopenia, & anemia?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • a,d

    Which drugs have a good VD; can cross into CSF & ocular tissue?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • a,c,d

    Which drugs can cause hypospermia?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • d

    Which drug's bioavailability increases when taken with fatty foods?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • d

    Which drug can cause retinal detachment?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • d

    Which drug can cause insomnia?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • a

    Which drug can cause anorexia?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • a, c, d

    Which drugs are teratogenic?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • b

    Which drug can have up to 28% of its dose deposited into the bone?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • b, c

    Which drugs are excreted in the urine?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • b

    Which drug is ONLY indicated for immunocompromised patients?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • b

    Which drug causes renal impairment in most of its patients?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • b

    Which drug can cause seizures to occur due to an electrolyte imbalance?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • c

    Which drug DOES NOT cross significantly into CSF?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • c

    Which drug requires probenecid & 1 L of NS with every treatment?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • Ganciclovir, valganciclovir

    Which drug(s) inhibits viral DNA synthesis via competitive binding of deoxyguanosine triphosphate? (2)

  • Foscarnet

    Which drug(s) uses a pyrophosphate analog that acts as a noncompetitive inhibitor of viral RNA & DNA polymerase?

  • Cidofovir

    Which drug(s) are a selective inhibitor of viral DNA synthesis?

  • c

    Which drug has a BBW for neutropenia?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • c

    Which drug has a BBW for dose-dependent nephrotoxicity?

    a) ganciclovir

    b) foscarnet

    c) cidofovir

    d) valganciclovir

  • virostatic

    All of our anti-CMV drugs are ________.