acyclovir, valacyclovir, famciclovir
What drugs are used against Herpes? (3)
acyclovir, valacyclovir
Which drug inhibits DNA elongation in the DNA polymerase through activity as a guanosine analog? (2)
Famciclovir
Which drug inhibits DNA synthesis and replication via HSV-2 polymerase?
b
Which uses IBW for dosing?
a) valacyclovir
b) acyclovir
c) Famciclovir
d) ganciclovir
a,c
Which is taken 2-3 times per day?
a) valacyclovir
b) acyclovir
c) Famciclovir
d) ganciclovir
b
Which is taken up to 5 days?
a) valacyclovir
b) acyclovir
c) Famciclovir
d) ganciclovir
b
Which can cause acute renal failure?
a) valacyclovir
b) acyclovir
c) Famciclovir
d) ganciclovir
a
Which can cause depression?
a) valacyclovir
b) acyclovir
c) Famciclovir
d) ganciclovir
a
Which can cause arthralgia?
a) valacyclovir
b) acyclovir
c) Famciclovir
d) ganciclovir
ganciclovir, valganciclovir, foscarnet, cidofovir
What are the anti-CMV drugs? (4)
c
Which is a prodrug?
a) valacyclovir
b) acyclovir
c) Famciclovir
d) ganciclovir
a,d
Which drugs have a BBW for thrombocytopenia, granulocytopenia, & anemia?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
a,d
Which drugs have a good VD; can cross into CSF & ocular tissue?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
a,c,d
Which drugs can cause hypospermia?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
d
Which drug's bioavailability increases when taken with fatty foods?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
d
Which drug can cause retinal detachment?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
d
Which drug can cause insomnia?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
a
Which drug can cause anorexia?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
a, c, d
Which drugs are teratogenic?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
b
Which drug can have up to 28% of its dose deposited into the bone?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
b, c
Which drugs are excreted in the urine?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
b
Which drug is ONLY indicated for immunocompromised patients?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
b
Which drug causes renal impairment in most of its patients?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
b
Which drug can cause seizures to occur due to an electrolyte imbalance?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
c
Which drug DOES NOT cross significantly into CSF?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
c
Which drug requires probenecid & 1 L of NS with every treatment?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
Ganciclovir, valganciclovir
Which drug(s) inhibits viral DNA synthesis via competitive binding of deoxyguanosine triphosphate? (2)
Foscarnet
Which drug(s) uses a pyrophosphate analog that acts as a noncompetitive inhibitor of viral RNA & DNA polymerase?
Cidofovir
Which drug(s) are a selective inhibitor of viral DNA synthesis?
c
Which drug has a BBW for neutropenia?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
c
Which drug has a BBW for dose-dependent nephrotoxicity?
a) ganciclovir
b) foscarnet
c) cidofovir
d) valganciclovir
virostatic
All of our anti-CMV drugs are ________.