Anita Akweshie-
an increase in BGC is detected by
the beta cells in the pancreas
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STEP 1; Intrusion
when the BGC is high glucose molecules enter the beta cells by facilitated diffusion
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STEP 2; respiration
the cells respire this glucose and produce ATP
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STEP 3 ; closed tunnels
high concentrations of ATP causes the potassium channels in the beta cells to close producing a change in the membrane potential
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STEP 4; gates open
the change in the membrane potential causes the voltage gated calcium channels to open
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STEP 5 ; insulin puke
in response to the influx of calcium ions the beta cells secrete the hormone insulin using vesicles
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what does insulin do
stimulates the uptake of glucose by muscle cells, fat cells , and the liver
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what are the target cells of insulin
cells which have glucose transporter proteins in their CSM
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the function of glucose transporter proteins
allow the uptake of glucose molecules via facilitated diffusion
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the rate of glucose uptake by cells is limited by
the number of glucose transporter proteins present in the CSM
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which cells are insulin-sensitive
target cells with glucose transporter proteins present
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the effect of insulin on target cells
stimulates them to activate/ add more glucose transport proteins to their CSM increasing their permeability to glucose which increases the rate of facilitated diffusion
