an increase in BGC is detected by
the beta cells in the pancreas
STEP 1; Intrusion
when the BGC is high glucose molecules enter the beta cells by facilitated diffusion
STEP 2; respiration
the cells respire this glucose and produce ATP
STEP 3 ; closed tunnels
high concentrations of ATP causes the potassium channels in the beta cells to close producing a change in the membrane potential
STEP 4; gates open
the change in the membrane potential causes the voltage gated calcium channels to open
STEP 5 ; insulin puke
in response to the influx of calcium ions the beta cells secrete the hormone insulin using vesicles
what does insulin do
stimulates the uptake of glucose by muscle cells, fat cells , and the liver
what are the target cells of insulin
cells which have glucose transporter proteins in their CSM
the function of glucose transporter proteins
allow the uptake of glucose molecules via facilitated diffusion
the rate of glucose uptake by cells is limited by
the number of glucose transporter proteins present in the CSM
which cells are insulin-sensitive
target cells with glucose transporter proteins present
the effect of insulin on target cells
stimulates them to activate/ add more glucose transport proteins to their CSM increasing their permeability to glucose which increases the rate of facilitated diffusion