Storage and Assembly:

•Splicing speckles are believed to function as storage and assembly compartments for splicing factors.

•These factors may accumulate in speckles when not actively engaged in splicing processes.

•The speckles serve as reservoirs where splicing factors can be stored before being transported to sites of active transcription when needed.

Regulation of Splicing Factor Access:

•Changes in cellular conditions, such as inhibition of transcription (and thereby splicing) or an increase in splicing activity,

•Can lead to alterations in the size and composition of splicing speckles.

Review: The Cell Nucleus (The Living Cell) UNFINISHED