a
Which sulfa drug is used to treat bacterial vaginosis?
a) AVC
b) sulfacetamide sodium
c) sulfisoxazole
d) sulfisoxazole acetate
b
Which sulfa drug is used to treat bacterial conjunctivitis?
a) AVC
b) sulfacetamide sodium
c) sulfisoxazole
d) sulfisoxazole acetate
c
Which sulfa drug is used to treat UTI?
a) AVC
b) sulfacetamide sodium
c) sulfisoxazole
d) sulfisoxazole acetate
c
Which sulfa drug is used to treat pediatric ear infections caused by Norcardia ?
a) AVC
b) sulfacetamide sodium
c) sulfisoxazole
d) sulfisoxazole acetate
d
Which sulfa drug is used to treat H.flu ear infections?
a) AVC
b) sulfacetamide sodium
c) sulfisoxazole
d) sulfisoxazole acetate
a
Which sulfa drug is used to treat minor UTI?
a) sulfamethizole
b) silver sulfadiazine
c) mefenide acetate
d) sulfasalazine
e) sulfamethoxazole
b,c
Which sulfa drug is used for the prevention of infection in wounds and burns?
a) sulfamethizole
b) silver sulfadiazine
c) mefenide acetate
d)sulfasalazine
e) sulfamethoxazole
c
Which sulfa drug can inhibit carbonic anyhydrase and lead to metabolic acidosis?
a) sulfamethizole
b) silver sulfadiazine
c) mefenide acetate
d) sulfasalazine
e) sulfamethoxazole
b
Which sulfa drug is especially active against Pseudomonas that may infect burn wounds?
a) sulfamethizole
b) silver sulfadiazine
c) mefenide acetate
d)sulfasalazine
e) sulfamethoxazole
d
Which sulfa drug is considered anti-inflammatory and inhibits prostaglandin synthesis in the GI tract? i.e. reduces diarrhea)
a) sulfamethizole
b) silver sulfadiazine
c) mefenide acetate
d)sulfasalazine
e) sulfamethoxazole
e
Which of the following sulfa drugs is used in conjunction with Trimethoprim?
a) sulfamethizole
b) silver sulfadiazine
c) mefenide acetate
d)sulfasalazine
e) sulfamethoxazole
b
Sulfamethoxazole is _____.
a) cidal
b) static
a
Trimethoprim is _____
a) cidal
b) static
gm-: ear infection, h.flu, uti
SMX-TMP combination therapy is 1st line for?
fungus
Pneumocystis Pneumonia is a ________.
Pneumocystis Pneumonia
SMX is the DOC for ?
displaces drugs from album; increasing their drug concentration except for cyclosporine
How does SMX affect drug concentrations of other drugs?
certain bacteria lack enzymes to synthesize folate
What are the inherent bacterial resistance mechanisms for Sulfonamide?
increased PAPA production, produce altered dihydropteroate, decreased permeability of sulfonamide into cell, MDR
What are the acquired bacterial resistance mechanisms for Sulfonamide?
decreased permeability of trimethoprim into cell, increased production of dihydrofolate reductase, altered dihydrofolate reductase enzyme
What are the acquired bacterial resistance mechanisms for Trimethoprim?
a
Which sulfa drug is used to treat Nocardiosis RTI and toxoplasmosis?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
a
Which sulfa drug can cause decreased carnitine levels that lead to mental changes?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
a
Which sulfa drug can cause leucopenia and anemia?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
b
Which drug is used as an alternate therapy in AIDS patients to treat Pneumocystis jiroveci pneumonia?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
c
Which drug is used in conjunction with Rifampin to treat Mycobacterium leprae?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
rash, fever, headache, photosensitivity, blood disorder
What are SE's associated with Dapsone?
c
Antacids and H2 blockers decreased absorption of ________.
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
d,e
Which drug is a prodrug?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
d
Which drug possesses several mechanisms to slow down bacterial resistance?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
e
Which drug requires acidic urine pH? Commonly advised to drink Vit C & Cranberry Juice.
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
f
Which drug inhibits phosphoenolpyruvate transferase enzyme that catalyzes formation of diphosphate-N-acetylmuramic acid that is needed for cell wall formation?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine
d
Which drug is used to treat SMX-TMP/ FQ resistant E.coli?
a) sulfadiazine
b) trimetrexate glucuronate
c) dapsone
d) Nitrofurantoin
e) Methenamine
f) Fosfomycin tromethamine