Ribonuclease inhibitor (RI) is a large (~450 residues, ~49 kDa), acidic (pI ~4.7), leucine-rich repeat protein that forms extremely tight complexes with certain ribonucleases.
Thelephoric acid
Thelephoric acid is a terphenylquinone pigment that is found in several fungi, such as Omphalotus subilludens and Polyozellus multiplex.
UK-414,495
UK-414,495 is a drug developed by Pfizer for the treatment of female sexual arousal disorder.
Ecallantide
Ecallantide (trade name Kalbitor, investigational name DX-88) is a drug used for the treatment of hereditary angioedema (HAE) and in the prevention of blood loss in cardiothoracic surgery.
Rhc80267
RHC80267 is an inhibitor of diacylglycerol lipase.
Talopeptin
Talopeptin is a chemical compound derived from cultures of Streptomyces.
PUGNAc
PUGNAc is a 1,5-hydroximolactone, acting as an inhibitor of a variety of N-acetylhexosaminidases.
Migalastat
Migalastat (INN/USAN, or 1-deoxygalactonojirimycin, trade name Galafold) is a drug for the treatment of Fabry disease, a rare genetic disorder.
GM6001
GM6001 also known as galardin or ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.
Lipstatin
Lipstatin is a potent, irreversible inhibitor of pancreatic lipase.
Cilastatin
Cilastatin is a chemical compound which inhibits the human enzyme dehydropeptidase.
Batimastat
Batimastat (INN/USAN, codenamed BB-94) is an anticancer drug that belongs to the family of drugs called angiogenesis inhibitors.
Phosphoramidon
Phosphoramidon is a chemical compound derived from cultures of Streptomyces tanashiensis.
Cipemastat
Cipemastat (rINN, also known as Ro 32-3555 and by the tentative trade name Trocade) is a selective inhibitor of matrix metalloproteinase-1 that has been investigated as an anti-arthritis agent.
Thapsigargin
Thapsigargin is non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA).
Ethyl protocatechuate
Ethyl protocatechuate is a phenolic compound.
Marimastat
Marimastat was a proposed antineoplastic drug developed by British Biotech.
S-17092
S-17092 is a drug which acts as a selective inhibitor of the enzyme prolyl endopeptidase.
Sivelestat
Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase.