0.7
What is the bioavailability of Digoxin tablets?
1
What is the bioavailability of Digoxin IV?
two-compartment
What kind of distribution does Digoxin exhibit?
f; distributes a lot into skeletal muscle
Digoxin distributes well into fat. T/F?
central compartment doesn't include myocardium; delayed onset of action
Why are serum samples useless during the distribution phase?
6-8 hrs
What's the minimum amount of time to collect serum samples?
36 hrs
How long is Digoxin's Half-life?
b
What is the most important pharmacokinetic parameter with Digoxin?
a) Volume of Distribution
b) Clearance
c) F
d) Steady State
albumin; 20-25
Digoxin binds to ______ at about _______ percent.
> 12 hrs
When is the best time to collect Digoxin samples?
40 ml/min
What is the CL is a patient has no/ mild HF?
20 ml/min
What is the CL if a patient has moderate to severe heart failure
(NYHA Class III or IV) ?