beta-lactam
MOA?
contains positive charge in side chain; blocks positively charged reaction intermediate for hydrolysis
Chemistry?
Gm + & some Gm -
Spectrum?
e.coli, h.flu, salmonella
What Gm (-) species are these antibiotics active against?
penetrates outer membrane of gm -; affinity for gm- PBP
Method of resistance?
rash, diarrhea
General SE?
a
Which antibiotic(s) are available as IV/IM & PO?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
a
Which antibiotic(s) is not used for hospital-acquired infections?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
ampicillin + sulbactam
Unasyn is a combination of what antibiotics?
c
Which antibiotics are used for less severe RTI & otitis media in children?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
a
Which antibiotic is used to treat moderate-severe RTI, S/SSI, GI, and UTI?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
b
Which antibiotic is only available as either IV or IM?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
a
Which antibiotic causes severe diarrhea?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
c
Which antibiotic can be used to treat some Gm- bacteria including lyme disease?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
amoxicillin + k clavulanate
Augmentin is a combination of what antibiotic & beta-lactamase inhibitor?
d
Which antibiotic is used for Pen'ase + resistant strains of H.flu, RTI, Otitis Media?
a) Ampicillin
b) Unasyn
c) Amoxicillin
d) Augmentin
amoxicillin; hydroxylation of phenyl
What chemical modification was done to ______ to improve its GI absorption?
streptococcus
Which Gm (+) bacteria are aminopens used on the most?