PROTEIN SYNTHESIS What does protein synthesis mean? What do proteins do? PROTEIN SYNTHESIS Transcription=Making RNA from DNA RNA processing Translation=Making protein from RNA 3 STEPS TO MAKE PROTEINS We have talked all about DNA, but what is RNA? RNA carries instructions from DNA to make proteins RNA 1) DNA sugar is deoxyribose; RNA sugar is ribose 2) DNA has thymine; RNA has uracil 3) DNA is double stranded; RNA is single stranded ACTIVITY: Take a moment to draw a Venn diagram showing the similarities & differences between DNA & RNA HOW DOES RNA DIFFER FROM DNA? TRANSCRIPTION & TRANSLATION OVERVIEW Strand of DNA used to copy complimentary RNA strand Controlled by enzyme called RNA polymerase Enzyme separates the DNA double helix and begin reading one of the strands of DNA That one strand of DNA is used to make pre-mRNA (messenger RNA) If the strand of DNA being used to make mRNA is: TACCGTGAAT What is the complimentary pre-mRNA strand that is made? HOW TO MAKE RNA MOLECULE Complete only the complimentary pre-mRNA strand on the worksheet! LET’S PRACTICE SOME MORE! pre-mRNA strand has to be cleaned up to become mRNA 2 types of sections Introns=sections that are taken out Exons=sections that are kept and come together to form a mature mRNA strand RNA PROCESSING MAKING PROTEIN tRNA=transfer RNA Brings the parts to make a protein based on the mRNA instructions Proteins are strings of molecules called amino acids tRNA gets the correct amino acid to the mRNA to build the string tRNA Groups of three nucleotides carried on the mRNA strand Codes for the anticodon carried on tRNA CODONS LET’S TAKE A LOOK AT THE ENTIRE PROCESS! THE ENTIRE PROCESS (TRANSCRIPTION & TRANSLATION)