Reviews en zoekstrategie workshop systematisch literatuurzoeken Centrale Medische Bibliotheek 2014 www.rug.nl/umcg/bibliotheek Narrative review Meta-analysis A review Evidence-based review Systematic review Comprehensive overview Systematic qualitative review 2 Fibromyalgia. Chakrabarty S, Zoorob R. Am Fam Physician. 2007 Jul 15;76(2):247-54. Fibromyalgia is an idiopathic, chronic, nonarticular pain syndrome with generalized tender points. It is a multisystem disease characterized by sleep disturbance, fatigue, headache, morning stiffness, paresthesias, and anxiety. Nearly 2 percent of the general population in the United States suffers from fibromyalgia, with females of middle age being at increased risk. The diagnosis is primarily based on the presence of widespread pain for a period of at least three months and the presence of 11 tender points among 18 specific anatomic sites. There are certain comorbid conditions that overlap with, and also may be confused with, fibromyalgia. Recently there has been improved recognition and understanding of fibromyalgia. Although there are no guidelines for treatment, there is evidence that a multidimensional approach with patient education, cognitive behavior therapy, exercise, physical therapy, and pharmacologic therapy can be effective. 3 Efficacy of Cognitive-Behavioral Therapies in Fibromyalgia Syndrome - A Systematic Review and Metaanalysis of Randomized Controlled Trials. Bernardy K, Füber N, Köllner V, Häuser W. J Rheumatol. 2010 Aug 3. [Epub ahead of print] OBJECTIVE: We performed the first systematic review with metaanalysis of the efficacy of cognitive-behavioral therapies (CBT) in fibromyalgia syndrome (FM). METHODS: We screened Cochrane Library, Medline, PsychINFO, and Scopus (through June 2009) and the reference sections of original studies and systematic reviews for CBT in FM. Randomized controlled trials (RCT) comparing CBT to controls were analyzed. Primary outcomes were pain, sleep, fatigue, and health-related quality of life (HRQOL). Secondary outcomes were depressed mood, self-efficacy pain, and healthcare-seeking behavior. Effects were summarized using standardized mean differences (SMD). (…) 4 Een zoekstrategie bouwen hoe doe je dat? nauw breed Zoekstrategie klein groot Zoekresultaat Een voorbeeld Internet-treatment for (reducing) alcohol drinking/ alcohol related disorders Alcohol drinking Internet intervention Randomized controlled trials Stap 1: concepten zoekstrategie Alcohol drinking Internet therapies randomized controlled trials Stap 2: zoektermen per concept Health care workers MeSH Textwoorden Influenza vaccinatie ouderen Hoe kom je aan zoektermen? pilot-searches! selecteer relevante titels bekijk indexering (MeSH) Start “omgekeerd”: begin met wat je al hebt Health care workers "Health Personnel"[Mesh] Influenza vaccinatie Ouderen "Influenza Vaccines"[Mesh] "Aged"[Mesh] "Influenza, Human"[Mesh] + "Vaccination"[Mesh] "Vaccines"[Mesh] Health care worker* Medical staff Nursing staff Nurses … influenza vaccination* influenza immunization* influenza immunisation* flu vaccination* … aged elderly older people older patient* … Voorbeeld Medical Subject Heading All MeSH Categories Persons Category Persons Age Groups Adult Aged Aged, 80 and over Frail Elderly Stap 3: Zoektermen combineren Boolean operators AND OR NOT (concept) zoekstrategie PubMed #1 #2 #3 "Health Personnel"[Mesh] Health care worker*[TIAB] OR Medical staff[TIAB] (#1 OR #2) 1e string #4 #5 "Influenza Vaccines"[Mesh] #6 #7 #8 #9 "Influenza, Human"[Mesh] AND ("Vaccination"[Mesh] OR "Vaccines"[Mesh]) (influenza[TIAB] OR flu[TIAB]) AND (vaccination*[TIAB] OR immunization*[TIAB] OR immunisation*[TIAB]) (#4 OR #5 OR #6) 2e string #10 "Aged"[Mesh] aged[TIAB] OR elderly[TIAB] OR older people[TIAB] OR older patient*[TIAB] (#8 OR #9) 3e string #11 (#3 AND #7 AND #10) combinatie van strings 1, 2 en 3 Opdracht 1 Smart drugs Review effectiviteit van “smart drugs” (neurocognitieverbeterende middelen) bij gezonde/ niet-zieke mensen. Pilot search: smart drugs for cognitive enhancement Probeer mbv het resultaat van de pilot search zoektermen te vinden (MeSH en textwoorden) voor “smart drugs” PubMed notaties en tools "heart rate"[MeSH Terms] MeSH, geexploeerd Index terms “heart rate”[MeSH:NoExp] MeSH, niet geexplodeerd Heart* Truncatie (het sterretje vervangt één of heart rate* meerdere karakters) Prase search (NB niet mogelijk: “heart rate” “heart rate*”) heart rate*[TIAB] Title, abstract heart rate*[tw] textword =ti, ab, AUkeyw, MESH Heart [AU] Author Heart rate*[all fields] Ti, author, inst, ab, Aukeyw, Search fields MESH AND, OR, NOT Boolean operators geen proximity operators Embase.com (gebruik Advanced search. Automated mapping uitzetten door weghalen bovenste 2 vinkjes (“map to..” en “include..”)! 'heart rate'/exp 'heart rate'/de Heart AND rate* EMTREE term, geexploeerd EMTREE term, niet geexplodeerd Truncatie (NB niet mogelijk: 2 bijelkaar horende termen trunceren zoals heart rate* in PubMed, omdat Embase de termen uit elkaar trekt. Oplossing: ‘heart rate’ OR ‘heart rates’ ‘heart rate’ Phrase search ‘heart rate’:ab,ti ‘heart rate’:ab,ti, de heart:au ‘heart’ Search Fields Title, abstract ti, ab, descriptor ) Author Ti, author, institute, ab, keywords AND, OR, NOT NEXT/n Boolean operators Proximity operators Cinahl (EBSCO) ook via EBSCO: PsycINFO, Medline (MH "Heart Rate+") Cinahl headings, geexploeerd (MH "Heart Rate") Cinahl headings, niet geexpl. “heart rate” Truncatie Prase search (dubbele aanhalingstekens kunnen ook worden weggelaten, geeft zelfde resultaat) TI heart rate* or AB heart rate* Title, abstract TX heart rate* Textwoorden AND, OR, NOT Boolean operators NEAR, WITHIN Proximity operators heart rate* Meer databases Cochrane Library Cochrane reviews, clinical trials Embase biomedisch, farmacologie PsycINFO Psychologie Cinahl Verpleegkunde, psychosociaal ERIC educatie, pedagogiek Web of Science SCI, SSCI citations PiCarta oa NL tijdschriftartikelen Vraag de CMB om advies Oefening 2: zoektermen omzetten naar een andere database 20 Stap 4: methodologische filters Gevalideerde “zoekstrings” gericht op vinden van bepaalde onderzoeksdesigns (bv gerandomiseerd of observationeel onderzoek) Bv PubMed filter Therapy/narrow (Haynes RB e.a.) Stap 5: Evalueren & verbeteren Dit is een cruciale stap bij het ontwikkelen van een goede strategie Evalueren & verbeteren 1. zoekresultaat behapbaar? 2. worden alle (bekende) relevante titels gevonden met de zoekstrategie? 3. Leveren checks (referentielijsten, related citations) géén extra relevante titels meer op? “Nee”? zoekstrategie verbeteren! Save search Tips Persoonlijk account per database datum in search name Backup in bijvoorbeeld Word Aanvullende zoekmethoden Referentielijsten Handsearching Experts, fabrikanten mailen (ongepubliceerde studies) Clinical trial registers (ongepubliceerde studies) Google Beschrijving van zoekstrategie Naam databases Last search update Restricties Zoektermen Aanvullende zoekmethoden Praktijkvoorbeeld systematic review Meer weten? PRISMA Statement Cochrane Handbook for systematic reviewers CRD's guidance for undertaking systematic reviews Advies CMB (mailen, afspraak) s.van.der.werf@umcg.nl / cmb@umcg.nl www.rug.nl/umcg/bibliotheek Oefening 3: zoekstrings combineren & zoekstrategie evalueren 28