Name:________________________________________________________Date:_________Class:_________
Chromosomal Disorders
You will research and present about a chromosomal disorder. As you do your research, please use reputable and
current resources which should be cited.
Potential Disorders to Research:
Down syndrome
Klinefelter’s syndrome
Cri du Chat syndrome
Turner’s syndrome
Patau’s syndrome
Edwards syndrome
Fragile X syndrome
Williams syndrome
Prader-Willi syndrome
Angelman syndrome
Emanuel syndrome
Ewing Sarcoma
Jacobsen syndrome
Potocki-Shaffer syndrome
Koolen-de Vries syndrome
Miller-Dieker syndrome
FOXG1 syndrome
Langer-Giedion Syndrome
Wolf-Hirschhorn syndrome
Your research/presentation should include the following information and:
 Name and Description of Disorder Include a full description of genetic disorder with detailed
information written in simple terms that the general public could understand.
 Cause/ Chromosomes Involved: Explain the specific type of the chromosomal anomaly involved
(e.g.. "Patients with trisomy 21 have an extra copy of 21st chromosome"). If you can explain how
meiosis goes wrong to cause your disorder, please do so.
 Prevalence and Frequency:
o How often does this occur in the population?
o Is it more frequent among men or women?
o Are there any known contributing factors (age of mother, family history, etc.?)
 Symptoms: What are the symptoms of this condition? Include a thorough description.
 Treatment:
o What types of treatments are available for patients who have the disease? If none, explain why.
o What is the life expectancy for patients with the disorder?
 Other interesting facts: Please include additional interesting facts you learned that are not already
mentioned elsewhere in your project.
 A Good Presentation:
o Should have a clear beginning, middle and end
o Exhibits good oral communications skills:
 A “4” on the communication strands states: “-My command of language skill is superior. I am
professional, fluent, and engaging to the audience. -Maintains eye contact -Superior body languageExtremely well prepared and organized”
o May include relevant pictures, data tables, graphs, video clips, etc. to support your claim. Those
visuals should be:
 Easy to follow & flow with your presentation
 Used to jog your memory and keep you on track; you should not read your presentation
from them
Presenter’s Name:
Evaluator’s Name:
Disorder Selected:
Description
Analysis
Communication
Advanced
Uses specific, relevant,
and accurate evidence,
creating a strong
foundation for the
argument.
Clearly and efficiently
breaks down and
elaborates on meaning
and significance of each
piece of evidence.
Proficient
Uses specific, relevant,
and accurate evidence,
creating a foundation for
the argument.
My command of
language skill is
superior. I am
professional, fluent, and
engaging to the
audience.
My command of
language skill is above
average. I demonstrate
above average
professionalism and
fluency, and I am
engaging to the
audience.
Breaks down and
elaborates on meaning
and significance of each
piece of evidence.
Satisfactory
Uses limited and/or
general evidence; may lack
relevance and/or accuracy,
creating a weak foundation
for the argument.
Breaks down evidence but
provides limited meaning
and significance.
Needs Improvement
Attempts to use
evidence, but is
insufficient in creating a
foundation for the
argument.
Breaks down evidence in
a confusing or
incomplete manner.
My command of language
skill is inconsistent. I
attempt to be professional
and fluent, but I may not
consistently engage the
audience.
My command of
language skill is lacking.
I demonstrate a
deficiency in being
professional and fluent,
and I am largely
disengaging to the
audience.
Positive comments (what they did well):
Constructive comments (what they need to improve upon):
Presenter’s Name:
Evaluator’s Name:
Disorder Selected:
Description
Analysis
Communication
Advanced
Uses specific, relevant,
and accurate evidence,
creating a strong
foundation for the
argument.
Clearly and efficiently
breaks down and
elaborates on meaning
and significance of each
piece of evidence.
Proficient
Uses specific, relevant,
and accurate evidence,
creating a foundation for
the argument.
My command of
language skill is
superior. I am
professional, fluent, and
engaging to the
audience.
My command of
language skill is above
average. I demonstrate
above average
professionalism and
fluency, and I am
engaging to the
audience.
Breaks down and
elaborates on meaning
and significance of each
piece of evidence.
Positive comments (what they did well):
Constructive comments (what they need to improve upon):
Satisfactory
Uses limited and/or
general evidence; may lack
relevance and/or accuracy,
creating a weak foundation
for the argument.
Breaks down evidence but
provides limited meaning
and significance.
Needs Improvement
Attempts to use
evidence, but is
insufficient in creating a
foundation for the
argument.
Breaks down evidence in
a confusing or
incomplete manner.
My command of language
skill is inconsistent. I
attempt to be professional
and fluent, but I may not
consistently engage the
audience.
My command of
language skill is lacking.
I demonstrate a
deficiency in being
professional and fluent,
and I am largely
disengaging to the
audience.