CHAPTERS 7–9: BIOMOLECULE PRESENTATIONS Earning a degree in biochemistry is a rather broad accomplishment. The sub-disciplines within biochemistry are incredibly numerous, and an interest in one or two subcategories will develop. Soon, biochemists become experts on specific classes of biochemical molecules, or experts on specific biochemical processes. Chapters 7–9 provide a tremendous amount of detail on individual classes of biomolecules, and a few biochemical processes. We will cover this information using a less formal approach, with pairs of students giving short (5 min or less) informative presentations on the sections of the text. The presentations can be strictly informative, or can be interactive with fill-in-the blank spaces like Mr. Keith’s notes. You may also incorporate the use of ChemSketch, model kits or other reasonable resources to assist in describing your sections of the text. Chapter 7: Coenzymes and Vitamins Intro (instructor) o Types of cofactors (Figure 7.1) Essential ions Coenzymes o Reactive centers 7.1 (instructor) o Metal-activated enzymes o Metalloenzymes 7.2 o Cosubstrates o Prosthetic groups o Difference between vitamins and coenzymes 7.3 o ATP o S-Adenosylmethionine o Nucleotide-sugar coenzymes 7.4 o NAD+ o NADP+ 7.5 o FAD o FMN 7.6 o Coenzyme A 7.7 o Thiamine pyrophosphate 7.8 o Pyridoxal phosphate 7.9 o Biotin 7.10 o Tetrahydrofolate 7.11 o Cobalamin 7.12 o Lipoamide 7.13 o Lipid vitamins Vitamin A Vitamin B Vitamin D Vitamin E Vitamin K 7.14 o Ubiquinone 7.15 o Protein coenzymes 7.16 o Cytochromes Chapter 8: Carbohydrates Intro (instructor) o Monosaccharides, oligosaccharides, polysaccharides 8.1 (instructor) o Aldoses o Ketoses o Trioses 8.2 o Pyranoses o Furanoses o Cyclization mechanism 8.3 o Conformations of furanose rings (model kits?) o Conformations of pyranose rings (model kits?) 8.4 o Sugar phosphates o Deoxy sugars o Amino sugars o Sugar alcohols o Sugar acids o Ascorbic acid 8.5 o Disaccharides o Reducing and nonreducing sugars o Nucleosides and other glycosides 8.6 o Homoglycans and heteroglycans o Starch and glycogen o Celluose and chitin 8.7 o Glycoconjugates Proteoglycans Peptidoglycans Glycoproteins Chapter 9: Lipids and Membranes Intro (instructor) o Lipids 9.1 (instructor) o Structural diversity of lipids o Functional diversity of lipids 9.2 o Fatty acids Saturated, unsaturated, monounsaturated, polyunsaturated Common names Trans Fatty Acids and Margarine 9.3 o Triacylclycerols 9.4 o Glycerophospholipids 9.5 o Sphingolipids 9.6 o Steroids 9.7 o Other Lipids Waxes Eicosanoids Isoprenoids 9.8 o Membrane Overview Lipid Bilayers Fluid Mosaic Model Laboratory study of lipids (p 268269) 9.9 o Lipid Bilayers and Membranes Are Dynamic Structures 9.10 o Three Classes of Membrane Proteins 9.11 o Membrane Transport Thermodymamics of Membrane Transport Pores and Channels Passive Transport Active Transport Endocytosis and Exocytosis 9.12 o Transduction of Extracellular Signals G Proteins are Signal Transducers The Adenylyl Cyclase Signaling Pathway The Inositol-Phospholipid Signaling Pathway Receptor Tyrosine Kinases