Surveillance of HealthcareAssociated Infections 1. Explain the purpose or aims of surveillance. 2. Discuss how to establish a system for healthcare-associated infection surveillance. 3. Differentiate between continuous surveillance and periodic prevalence surveys. December 1, 2013 Learning Objectives 2 • 45 minutes December 1, 2013 Time involved 3 The systematic observation of the occurrence and distribution of disease within a population and of the events that increase or decrease the risk of the disease occurrence December 1, 2013 What is Surveillance? 4 Identification of problems and prioritising infection prevention and control (IP&C) activities Assisting the development of IP&C policies and associated clinical practices Detecting changes in the endemicity of an HAI or an adverse event Detecting changes in compliance with IP&C policies Detecting outbreaks of adverse events December 1, 2013 Aims of HAI Surveillance - 1 5 Establishing the effectiveness of an intervention Identifying whether the current program meets benchmarks Establishing data for an evidence-based plan to improve care and to meet accreditation or regulatory requirements December 1, 2013 Aims of HAI Surveillance - 2 6 Infection surveillance framework includes: Assessing the population Selecting the outcome or process for surveillance Using surveillance definitions Collecting surveillance data Calculating and analyzing surveillance rates Applying risk stratification Reporting and using surveillance information December 1, 2013 Establishing a Framework for Surveillance 7 Assessment should evaluate: 1. 2. 3. 4. High risk populations High volume procedures, interventions High impact infections High cost infections December 1, 2013 Assessment of the Population 8 • Outcome Surveillance • Decreasing risk and costs • Identify gaps December 1, 2013 Outcome vs. Process • Process Surveillance • Identify care delivery issues 9 Is it necessary to survey the entire health care facility or only focus on high-risk patient groups or procedures or commonly performed procedures? Have rates increased in certain groups/procedures /interventions? What is the most important IP&C-related process that is likely to be associated with this rate? How will a standard, validated, and reproducible definition of infection be applied? December 1, 2013 What to consider in establishing a surveillance framework - 1 10 Should continuous surveillance or point prevalence surveys be used? How will the data be collected, stored, retrieved, summarized, and interpreted? How will results to clinicians be provided in a timely manner? How will the information be used to continue to lower infection rates? December 1, 2013 What to consider in establishing a surveillance framework - 2 11 Continuous surveillance or periodic prevalence surveys Alert-based surveillance Post-discharge surveillance December 1, 2013 Types of Surveillance 12 Undertaken prospectively Best way to establish trends and distribution of HAI incidence Can be active, passive, or a combination of both Active surveillance involves daily visits to patient wards/care units to assess patients atrisk of HAI December 1, 2013 Continuous Surveillance - 1 13 Case finding using active and passive surveillance by an IP&C practitioner increases correct detection of HAIs Only incidence cases of HAI should be reported December 1, 2013 Continuous Surveillance - 2 14 A good substitute for continuous surveillance Performed on a single day or week Can show the magnitude of HAI, highlight problems requiring more investigation, and identify changing patterns of HAIs Can be used to target areas or services where infection rates are suspected to be high December 1, 2013 Prevalence Surveys 15 Prevalence Survey: Line listing Month/quarter Year Resident/patient Identifiers Name December 1, 2013 Area: _______________________________________ HAI HAI (No=0/Yes=1) Antibiotic Bed Number Type of HAI Microorganism Treatment 16 Monitor specific clinical conditions surgical site infections caused by Group A Streptococcus meningococcal meningitis December 1, 2013 Alert-based Surveillance - 1 Is a part of the ICP team daily work Aims to warn of early outbreaks and allow rapid control procedures 17 Alert organism surveillance Continuous monitoring of specific microorganisms identified by the microbiology laboratory December 1, 2013 Alert-based Surveillance - 2 Simple and cheap, and can be automated in computerised laboratories Can show trends of specific microorganisms in different wards over time Allows the IP&C team to formulate preventive actions 18 A method of identifying patients with a HAI after leaving the facility Often used for surgical site infection (SSI) detection Will identify more infections and therefore yield a higher SSI rate December 1, 2013 Post-discharge Surveillance 19 A letter sent home with the patient to complete and return A questionnaire to the patients’ medical practitioner December 1, 2013 How to Conduct PostDischarge Surveillance 20 An infection occurring during the process of care in a health-care facility which was not present or incubating at the time of admission Includes infections acquired in the health-care facility but appearing after discharge and also occupational infections among health-care workers A cut-off point 48 hours after admission is typically used to distinguish between HAI and community infections December 1, 2013 Definitions for HAI 21 Infection rates vary according to the definition used Comparisons should only be made if the same set of definitions is used and applied in exactly the same manner More meaningful to use surveillance data from same institution to measure trends to alert staff of increasing problems to monitor the effectiveness of interventions December 1, 2013 What are standards or thresholds for HAI rates? 22 Rates are calculated with a numerator (number of persons with the infection) divided by a denominator (number of persons at risk for the infection) December 1, 2013 Surveillance Statistics: Rates 23 Incidence rate (%) No. of patients diagnosed with new HAI during the surveillance period x 100 No. of patients at-risk of HAI during the same period December 1, 2013 Incidence Rate 24 • The number of cases of active HAI in a defined patient population • May be new cases or ones that developed before the survey timeframe and are still active • Prevalence rate December 1, 2013 Prevalence Rate - 1 • the proportion of patients in the population who have an active infection at the time of the survey 25 Number of new and existing cases of specific HAI during the specified survey period x 100 Total number of patients surveyed for HAI during the specified survey period December 1, 2013 Prevalence Rate - 2 26 Based on an accumulation of person-time units with a statistically rare numerator (e.g., CLABSI) Convention is to multiply the proportion by 1,000 to be expressed as per 1,000 patient/bed/catheter days December 1, 2013 Incidence Density Rates Calculation of Incidence density number of new specific HAI during the surveillance reporting period Person-time of susceptible patients at risk during the same surveillance period x 1000 27 Number of devices per number of patient-days A measure of the total patient-days in which a high-risk device was used Can be used as a marker for risk of infection Calculate the utilisation ratios for each unit with a denominator that reflects only those patients at-risk December 1, 2013 Utilisation Ratio 28 Urinary catheter utilisation ratio = Total number of urinary catheter-days Total number of patient-days December 1, 2013 Calculation of Utilisation Ratio Central catheter utilisation ratio = Total number of central catheter-days Total number of patient-days 29 Number device-associated infections for a site x 1,000 Number of device-days December 1, 2013 Device-Associated Infection Rates Infection rate per 1,000 device-days 30 Number of catheter-associated UTI x 1000 Number of catheter-days December 1, 2013 Catheter-Associated Urinary Tract Infection Rate Infection rate of catheter-associated UTI per 1000 catheter-days 31 Incidence data usually analysed periodically to establish rates Typically calculated at the end of every month or quarter Prevalence data analysed immediately at the end of the survey to establish a rate that reflects that survey period December 1, 2013 Frequency of Data Analysis 32 There should be a written surveillance plan for the health care facility including definitions used how data are collected the frequency of data collection who is responsible for surveillance activities December 1, 2013 Summary - 1 Surveillance activities should support a system that can identify risk factors for infection and other adverse events implement risk-reduction measures monitor the effectiveness of interventions 33 Surveillance plays a critical role in identifying outbreaks, emerging infectious diseases, antibiotic-resistance organisms, and bioterrorist events so that infection prevention and control measures can be instituted Surveillance program in healthcare organisations should be integrated to include infection prevention, performance improvement, patient safety and public health activities December 1, 2013 Summary - 2 34 • Lee TB, et al. Recommended practices for surveillance: Association for Professionals in Infection Control and Epidemiology (APIC), Inc. Am J Infect Control 2007; 35: 427-440. • McLaws ML, Taylor P. The Hospital Infection Standardised Surveillance (HISS) programme: analysis of a two-year pilot. J Hosp Infect 2003; 53 (4): 260-268. • Best Practices for Surveillance of Health Care-Associated Infections, 2008, Ontario Ministry of Health and Long-Term Care/Public Health Division/Provincial Infectious Diseases Advisory Committee, Canada. http://www.health.gov.on.ca/patient_safety/pro/cdad/toolkit_ricn/r ep_pidac_hai_best_prac.pdf • European Centre for Disease Prevention and Control. Surveillance http://www.ecdc.europa.eu/en/activities/surveillance/Pages/Activiti es_Surveillance.aspx • VICNISS Hospital Acquired Infection Surveillance System. State Government Victoria, Australia. http://www.vicniss.org.au/ December 1, 2013 References 35 Epi Info, a free software package can be downloaded from the Centers for Diseases Control and Prevention, http://wwwn.cdc.gov/epiinfo/html/downloads.htm, with a desktop calculator version accessed from http://wwwn.cdc.gov/epiinfo/html/prevVersion.htm. December 1, 2013 Epi Info Alternatively, a free calculator written in Excel is available at www.pedro.org.au/wp-content/uploads/CIcalculator.xls 36 1. The purposes of establishing an HAI surveillance system include which of the following? a. b. c. d. Identification of HAI problems within an organization Detecting outbreaks of HAIs Establishing data for improving patient outcomes All of the above December 1, 2013 Quiz 2. Which of these types of surveillance can be used as a substitute for continuous surveillance of HAIs? a. b. c. d. Post discharge Alert based Prevalence Prospective 3. A written surveillance plan is an important component of the infection prevention and control programme. (T/F). 37 • IFIC’s mission is to facilitate international networking in order to improve the prevention and control of healthcare associated infections worldwide. It is an umbrella organisation of societies and associations of healthcare professionals in infection control and related fields across the globe . • The goal of IFIC is to minimise the risk of infection within healthcare settings through development of a network of infection control organisations for communication, consensus building, education and sharing expertise. • For more information go to http://theific.org/ December 1, 2013 International Federation of Infection Control 38