Ch. 5: p. 130 Cardiovascular System at a Glance Functions of Cardiovascular (CV) System Distribute blood to all areas of body Delivery of needed substances to cells Removal of wastes Organs of Cardiovascular System Heart Arteries Capillaries Veins Cardiovascular Combining Forms angi/o vessel aort/o aorta arteri/o artery ather/o fatty substance atri/o atrium cardi/o heart coron/o heart hemangi/o blood vessel phleb/o vein sphygm/o pulse steth/o chest thromb/o clot valv/o valve valvul/o valve vascul/o blood vessel vas/o vessel, duct ven/o vein ventricul/o ventricle Cardiovascular System Suffixes –manometer instrument to measure pressure –ole small –tension pressure –ule small Anatomy and Physiology Also called circulatory system Maintains distribution of blood throughout body Delivers oxygen and nutrients like glucose and amino acids to cells Picks up carbon dioxide and other waste products from cells and delivers to lungs, liver, and kidneys for elimination Is composed of: Heart Blood vessels Arteries Capillaries Veins Divided into pulmonary circulation and systemic circulation Systemic Circulation Between heart and cells of body Carries oxygenated blood away from left side of heart to body Carries deoxygenated blood from body to right side of heart Pulmonary Circulation Between heart and lungs Carries deoxygenated blood away from right side of heart to lungs Carries oxygenated blood from lungs to left side of heart Heart Muscular pump Made up of cardiac muscle fibers Could be called a muscle instead of an organ Beats an average of 60 – 100 beats per minute (bpm), Each time the muscle contracts: Blood is ejected from heart Pushed throughout body within blood vessels Located in the mediastinum More to left side of chest Directly behind sternum About size of a fist Shaped like upside-down pear Tip of heart at lower edge Called the apex Heart Layers Endocardium Myocardium Epicardium Heart Chambers Divided into four chambers Two atria Two ventricles Heart is divided into right and left sides by a wall called the septum Atria Left and right upper chambers Receiving chambers Blood returns to atria in veins Superior and inferior vena cava Pulmonary veins Ventricles Left and right lower chambers Pumping chambers Thick myocardium Blood exits ventricles into arteries Aorta Pulmonary artery Heart Valves Four valves in heart Tricuspid, pulmonary, mitral, aortic Act as restraining gates to control direction of blood flow Found at entrance and exit to ventricles Allow blood to flow only in forward direction by blocking it from returning to previous chamber Tricuspid Valve 1 An atrioventricular valve Between right atrium and ventricle Prevents blood in ventricle from flowing back into atrium Has 3 leaflets or cusps Pulmonary Valve A semilunar valve Between right ventricle and pulmonary artery Prevents blood in artery from flowing back into ventricle Semilunar – valve looks like half moon Mitral Valve An atrioventricular valve Between left atrium and ventricle Prevents blood in ventricle from flowing back into atrium Also called bicuspid valve - has two cusps Aortic Valve A semilunar valve Between left ventricle and aorta Prevents blood in aorta from flowing back into ventricle Path of Blood Flow Through Heart 1. Deoxygenated blood from body enters relaxed right atrium via two large veins called: Superior vena cava Inferior vena cava 2. Right atrium contracts Blood flows through tricuspid valve into relaxed right ventricle 3. Right ventricle contracts Blood is pumped through pulmonary valve into pulmonary artery Carries blood to lungs 4. Relaxed left atrium receives blood that has been oxygenated by lungs Blood enters left atrium from the four pulmonary veins 5. Left atrium contracts Blood flows through mitral valve into relaxed left ventricle 6. Left ventricle contracts Blood is pumped through the aortic valve and into aorta Largest artery in the body Carries blood to all parts of body Systole and Diastole Heart chambers alternate between: Relaxing to fill Contracting to push blood forward Relaxation phase is diastole Contraction phase is systole Conduction System of the Heart Autonomic nervous system controls heart rate Therefore, no voluntary control over heart Special heart tissue conducts electrical impulses Stimulate different chambers to contract in correct order Path of the Conduction System 1. Sinoatrial (SA) node, or pacemaker, is where electrical impulse begins From SA node a wave of electricity travels through atria Causing them to contract, or go into systole 2. Next, atrioventricular node (AV) is stimulated 3. This node transfers stimulation wave to bundle of His 4. Electrical wave travels down bundle branches within interventricular septum 5. Finally, Purkinje fibers in ventricular myocardium are stimulated Results in ventricular systole Blood Vessels Pipes that circulate blood through body Three types: Arteries Capillaries Veins Lumen is the channel within blood vessels Arteries Large thick-walled vessels Wall contains smooth muscle and can dilate or constrict As arteries travel through body they branch into progressively smaller vessels called arterioles Carry blood away from heart Towards either lungs or cells and tissues of body Pulmonary artery carries deoxygenated blood to lungs Aorta carries oxygenated blood to body Coronary arteries supply myocardium Capillaries Network of tiny, thin-walled blood vessels called a capillary bed Connecting unit between arteries and veins Arterial blood flows into capillary bed Venous blood flows out of capillary bed Location for: Oxygen and nutrients to diffuse out Carbon dioxide and wastes to diffuse in Veins Much thinner walls than arteries Much lower pressure system than in arteries Have valves to insure blood flows only towards heart Squeezing by skeletal muscles also assists blood return to heart 2 Smallest veins are called venules Veins Carry blood towards the heart From either the lungs or the cells and tissues of body Pulmonary veins carry oxygenated blood from lungs Superior and inferior vena cava carry deoxygenated blood from body Blood Pressure Measurement of force exerted by blood against walls of a vessel May be affected by several characteristics of blood and blood vessels Elasticity of arteries Diameter of blood vessels Viscosity of blood Volume of blood Amount of resistance to blood flow During ventricular systole Blood is under great pressure Gives highest pressure—systolic Top number of blood pressure reading During ventricular diastole Blood isn’t being pushed from heart at all Blood pressure drops to lowest point— diastolic Bottom number of blood pressure reading Word Building with angi/o Word Building with aort/o & arteri/o Word Building with ather/o & atri/o Word Building with cardi/o Word Building with coron/o, phleb/o, and vascul/o Word Building with valv/o & valvul/o Word Building with ven/o & ventricul/o Abbreviations: p. 152 AFB AMI ASD AV BP Bpm CABG CAD Cath CCU CHF CPK CPR CV ECG,EKG ECHO HTN ICU IV MI mmHG MVP Vfib VSD VT Heart & Blood Vessel Pathology p. 144-148 Clinical Laboratory Tests: p. 148-149 Cardiac enzymes, Serum lipoprotein level, angiography, cardiac scan, Doppler ultrasonography, echocardiography, venography Cardiac Function Tests: Cardiac catheterization, EKG, Holter monitor, stress testing Medical Procedures p. 150 CPR, defibrillation, pacemaker implantation Surgical Procedures P. 150-151 CABG, heart transplant, intracoronary artery stent, PTCA, valve replacement Cardiovascular Pharmacology p. 151-152 Anticoagulants, Antilipidemic, Beta blocker, diuretic, thrombolytic 3