UNIT 3 – MOLECULAR GENETICS PLANNING PATHWAY DAY 1. 2. TOPIC (LESSON) Introduction to Molecular genetics; - Are you ready questions on pages 266 to 267 - Read Chap 6 opener and work on Starting point questions 1 to 4 on page 268. - Mini Investigation on page 269: Build a DNA Model. (Modified) (Use DNA Models). - The Molecular Basis of Inheritance (pages 270 to 272) DNA: The hereditary Material - History, the discovery and location of DNA (note) - Design an experiment – Isolation and quantification of DNA page 300. Investigation 6.2.2. 3. Structure of the DNA molecule - Chemical composition – nucleotides - The double helix ) Wilkins and Franklin, Watson and Crick - The collaborative nature of Science (page 278) 4. Isolation and quantification of DNA - Conduct the lab 5 and 6 7. DNA Replication and repair - Overhead notes (key players i.e. proteins) - DNA replication semi-conservative model (notes) DNA Organization in Eukaryotes and Prokaryotes - The Packing of Eukaryotic DNA - Prokaryotic DNA - Telomeres: A key Difference DNA Replication and Aging - Role of telomeres During Replication - Telomeres and aging - Telomeres and Cancer: When Cells Do not Age Chapter 6 test 8. COMMENTS, HOMEWORK, INCLUDING TIME SAVING STRATEGIES Homework: Complete any unfinished questions from Starting point questions 1 to 4 on page 268. Answer questions 1 to 6 on page 272. Start studying for the test now! Homework: In pairs, finish designing the experiment on page 300. Get ready for the lab activity on Day 4. Homework: Answer questions 1 to 6 on page 279. Work on collaborative nature of Science (Due on the day of the chapter 6 test) Announce Chap 6 test on day 7 Review questions for chapter 6 are on page 304 to 309 Homework: Answer the analyze and evaluate, and apply and extend questions on page 301 Homework: Answer questions 1 to 7 on page 290. Homework: answer questions 1 to 5 on page 294 and questions 1 to 7 on pages 298. Go over your notes too. This should be on going. Homework: Read chap 7 opener on page 310 and answer Starting point questions 1 to 4 on page 310. 9. Genes and Protein Synthesis Mini Investigation on page 311. Find a partner - Translating the code and answer questions A to E - From Gene to Proteins - One Gene-One Polypeptide Hypothesis (note) Homework: answer questions 1 to 6 on page 318. 10. Protein Synthesis Overview - The Central Dogma of Molecular Genetics - RNA – the Molecule - Compare and Contrast DNA and RNA - The Genetic Code - Start Studying – Unit Test at the End of the Unit! Transcription - Terms used in transcription - The process (initiation, elongation and termination) - Posttranscriptional modifications in eukaryotic cells Translation - The ribosome - The role of transfer RNA (tRNA) - Translation the process (initiation, elongation and termination) Controlling Gene Expression - Prokaryotic Gene Control Mechanisms - The lac Operon - The trp Operon - Eukaryotic Gene Control Mechanisms (Transcriptional, Post-Transcriptional, Translational and Post-Translational Regulation - Cancer Homework: Answer questions 7 to 12 on page 318 Genetic Mutations - Small Scale Mutations – Definition of Terms - Large scale Mutations - Causes of Genetic Mutations (chemical mutagens and radiation) - Positive or Negative Mutations? - Discover the Mutation exercise Genome and Gene Organization - Genome Components - Biodiversity and Genomes - You are Studying - Right? Viruses a Special Case Homework: answer questions 1 to 7 on page 345 Review Chapter 7 Answer questions 1 to 36 on pages 358 to 359 - Start Studying – Unit Test is Coming Soon Homework: Finish the questions for homework 11. 12. 13. 14. 15. 16. Homework: Answer questions 1 to 10 on page 324. Homework: Answer questions 1 to 8 on page 331 Homework: answer questions 1 to 9 on page 339 Homework: answer questions 1 to 8 on page 349 and questions 1 and 2 on page 353. 17 and 18. 19. 20. 21. Genetic Technologies (Biotechnology) - What is Biotechnology? - DNA palindromic Sequences (page 365) - Biotechnological tools and techniques (Restriction Endonucleoases (enzymes), Methylases, DNA Ligase, Gel Electrophoresis, Plasmids and Transformation Advanced Molecular Biological Techniques (DNA Sequencing) - The Polymerase Chain Reaction (PCR) - Restriction Fragment Length Polymorphism - DNA Sequencing Genetic Engineering Application - Medical - Agricultural - Forensics - The Future Biotechnology and Health - Gene Therapy: Correcting Genetic Disorders - Genetic screening Homework: answer questions 1 to 6 and 8 on page 375 Unit3 Test – (summative) Homework – Answer Are You Ready Questions for Unit 4 page 424 to 425 Homework: Answer Questions 1 to 9 on page 385 Homework: Answer questions 1 to 8 on page 394 Go over your notes and chapter and unit review questions