Experience, Expertise and a Commitment to Excellence™ Protons - Superior Dose Distribution 4 Relative Dose The Bragg Peak is representative of a delivery of a full, localized, and uniform dose of energy in the target 3 2 1 0 60 10 20 Depth in Tissue (cm) Experience, Expertise and a Commitment to Excellence™ 30 System Components The Synchrotron Accelerator The Beam Transport System The Stationary Beam Gantries (Isocentric Gantries) Patient Alignment and Digital Imaging Systems Facility Control System Experience, Expertise and a Commitment to Excellence™ Facility Layout The Loma Stationary Beam:Linda Has two branches: •Eye Tumors •Head and Neck Tumors The Injector: Protons are stripped out of the nucleus of hydrogen atoms and sent to the accelerator. Synchrotron: (Accelerator) A ring of magnets, 20 ft. in diameter, through which protons circulate in a vacuum tube. University Medical Center Proton Treatment Center The Gantries: Resembling giant ferris wheels can rotate around the patient and direct the proton beam to a precise point. Each gantry weights about 90 tons and stands 3 stories tall. It supports the bending and focusing magnets to direct the beam. Steelreinforced concrete walls are up to 15 feet thick. Beam Transport System: Carries the beam from the accelerator to one of four treatment rooms. This system consists of several bending Experience, Expertise andand a Commitment to Excellence™ focusing magnets which guide the beam around corners and focus it to the desired location. Proton Accelerator Control System Conforma 3000 Integrated Solution Treatment Control System (TCS) Accelerator Control System (ACS) Treatment Workstation Integrated and Automated “The Brain” Software & Electronics for Treatment Precision Accelerate Deliver Control Experience, Expertise and a Commitment to Excellence™ Accelerator Control - Advantages Automatic Beam Centering in Treatment Nozzle Key to Active Beam Scanning Rapid Beam Line Switching <10 sec. Accurate, Reproducible Beam Energy Within 0.1 MeV Patented Safety Systems Ensure Beam is Delivered at the Right Place & Time Experience, Expertise and a Commitment to Excellence™ Gantry Treatment Room Integrated and automated Rotates >360o Treatment from multiple “portals” or angles Isocenter is contained within a sphere to 1.0 mm in radius Automated set up Designed for functionality Experience, Expertise and a Commitment to Excellence™ Conforma 3000 Passive Scattering Beam Delivery System Compensator (Bolus) and Block (Aperture) Dose and Flatness Monitor(s) Range Modulation Wheel X-ray Tube Second Scatterer First Scatterer Profile Monitor Beam Movable Snout (cones) Experience, Expertise and a Commitment to Excellence™ Conforma 3000 Active Beam System Intensity Modulated Proton Therapy IMPT or Active Beam Scanning (ABS) Supports Compensator-less treatments Variable energy controls penetration depth Redundant Dose Detectors Capable of continuous (raster scanning) & discrete point based (“Spot” scanning) Optional Compensator (Bolus) and Block (Aperture) Beam Movable Snout (cones) Scanning Magnets Radiographic Imaging Panels (2) Experience, Expertise and a Commitment to Excellence™ Intensity Modulated Proton Therapy Ability to Treat Complex Volumes & Multiple Target Areas “Spot Scanning” Technique Beam scans from the top down Radiation deposited from side to side Experience, Expertise and a Commitment to Excellence™ Modular Design (4 gantry, 2 Stationary) Experience, Expertise and a Commitment to Excellence™ Treatment Planning Software Experience, Expertise and a Commitment to Excellence™ Contact Information Jon Slater, President & CEO 909.799.8333 slater@optivus.com Daryl Anderson Chief Financial Officer 909.799.8342 danderso@optivus.com David Lesyna VP Engineering 909.799.8312 lesyna@optivus.com Mike Martin VP of Sales 513.518.8037 mmartin@optivus.com Ken Rice Director of Computer Science 909.799.8318 rice@optivus.com www.optivus.com Experience, Expertise and a Commitment to Excellence™