Schistosomiasis
Control Initiative (SCI)
A brief overview of SCI past and current activities
SCI Open Day
June 27 2013
Director Professor Alan Fenwick OBE PhD
Department of Infectious Disease Epidemiology
Imperial College
Faculty of Medicine
St Mary’s
University of London
Welcome
Welcome to the members of the SCI Advisory Board
Chairman, Sir Roy Anderson
Justine Fraine
Clint Evans
Sam Zaramba
David Heymann
Stuart Smith
Richard Viner
Lorenzo Savioli
David Crompton
Lord Andrew Stone
Peter Dranfield
Apologies from Profs Neil Ferguson and Elio Riboli
Welcome to all present: guests, partners, and donors
and especially staff from overseas – Dr Narcis Kabatereine,
Dr Dhekra Annuzaili and from Ethiopia Oumer Shafi
The SCI aims to assist
implementation of
control of NTDs to
national scale in Africa
• Based at Imperial College London within the
School of Public Health
• Established in 2002
• SCI has moved through 4 phases
• 2002-07 Bill and Melinda Gates support
• 2007-10 Add in USAID/RTI, Geneva Global
• 2010-13 DFID plus private donations
• 2013 - Expansion towards elimination
Within the College
• Imperial College has “charity exempt”
status
• IC Trust gives us charity status in UK
• Our financial income is ring fenced
• UK Coalition against NTDs
• London Centre for NTDs
Recent wider funding sources
• GNNTDC funded projects in Uganda and Yemen (SCI Founder
member) – Yemen support now funded by ENDFUND
• Yemen World Bank partnership 2010-2015
• Gates funding (neuro-cysticercosis in 3 countries)
• ENDFUND/Geneva Global grant (2010-13) for Rwanda
• ENDFUND small grant for Zimbabwe
• DFID award ICOSA (2010-2015)
• SCORE – 3 grants for operational research (Mozambique and Niger)
(2010-2015)
• Sightsavers – partnership on mapping and implementation in Nigeria
• Private donations from US and UK public (ongoing)
Collaboration
Partnership with :
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•
•
•
•
•
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Developing World Health (fund raising)
PCD (Imperial College) - Ethiopia
Deworm the World (school health)
Sightsavers (UK NTD Coalition)
CNTD Liverpool (DFID ICOSA)
GSK (albendazole donation)
WHO and Merck Serono (pzq donation)
Natural History Museum/SCORE (Zanzibar)
SCORE (Niger and Mozambique)
www.givingwhatwecan.org
www.givewell.org
SCI control programmes in Africa 2012-2016
Yemen
World Bank and
ENDFUND
Mauritania
Niger
Senegal
Nigeria
Ethiopia
Liberia
Cote D’Ivoire
Rwanda – SCI/ENDFUND
Uganda
DRC
Tanzania
Malawi
Burundi
Zambia
Zim
Mapping and development of
control in DRC, Mauritania,
Senegal, Ethiopia, Zimbabwe
And Madagascar
Madagascar
Mozambique
June 2012 – June 2013
We have been implementing our praziquantel and
albendazole treatments in 8 countries as per DFID contract
in partnership with Liverpool and Crown Agents.
(75 million treatments over 5 years)
We have been collecting data and treating in Niger and
Mozambique as grantee partners in the SCORE project at
UGA
We now have in place 4 years funding for Burundi from a
private donor and ENDFUND support for Rwanda for 3
years. MoH carry out twice a year deworming of school
children and annual praziquantel treatment where
indicated
June 2012 - June 2013
Recommendations on their websites from both
www.Givingwhatwecan.org and www.Givewell.org
have led to generous donations from the British & US public.
With this funding we have:
• Assisted Senegal to expand mapping
• Assisted round 2 treatments in Yemen (10 million
treatments this year alone)
• Transfered funding to Ethiopia for
• 1.5 million treatments spread over all health regions Ethiopia,
• a launch of the national plan plus NTD symposium in Addis Ababa
in June 2013
• Pledged funding for schistososmaisis and STH mapping nationally
during 2013 with EHNRI,
Follow up from January 2012
Since the January 30th 2012 meeting in London (The London
Declaration):
• Meeting at World Bank in December 2012
• WHA resolution on elimination of NTDs May 2013
• Scorecard towards elimination developed
2012 and 2013 treatments
treated 2012:
Schisto/STH
Country
Funding
Burundi
Donor
Cote D'Ivoire
DFID
295,943, 295,943
3,026,719, 3,026,719
Ethiopia
Donor
0
1,500,000, 6,800,000
Liberia
DFID
17,400, 17,400
440,719, 440,719
Malawi
DFID
Mozambique
DFID
Niger
DFID
(SCORE/USAID)
Rwanda
ENDFUND
Senegal
Donor
450,000, 450,000
Tanzania
DFID
(Cysticercosis)
122,996, 122,996
2,276,453, 2,276,453
Uganda
DFID/GNNTDC
200,000, 200,000
700,000, 700,000
Yemen
World Bank GNNTDC
2,050,000 2,050,000
10 million, 10 million
Zambia
DFID
19,800, 19,800
650,000, 650,000
Zanzibar
DFID/ZEST
827,778, 827,778
1,037,672, 1,037,672
PZQ treatments
8,930,404
25,545,908
Deworming
12,130,404
37,245,908
Total
600,000 3,800,000
2,037,487 2,037,487
1,819,000 1,819,000
490,000 490,000
planned for 2013/14
600,000, 3,800,000
5,600,000, 5,600,000
3,664,345, 3,664,345
490,000 490,000
600,000 3,800,000
And the future ?
Elimination by 2020 ?
We plan to consolidate our support in each of the “SCI”
countries so that they reach and sustain national coverage
We will pursue fund raising opportunities as they arise to
increase resources going to NTD control
With increased support from DFID promised for 2013-2017
we anticipate a closer partnership with PCD and an
increase in treatments in the existing countries, plus
expansion into Ethiopia and DRC
We are working more closely with USAID and their
contractors, and with Deworm the World to avoid
duplication of donations
SCI Organogram
SCI Director
Professor Alan Fenwick
Director M
and E
Prof Joanne
Webster
Deputy
Director
Dr. Wendy
Harrison
Health
Economist
vacant
Senior
Biostatistician
Dr Sarah
Knowles
Programme
Manager
Dr Anna Phillips
(West Africa and
Mozambique)
Support staff
Finance
Kieran Bird
Shaivali Shah
Office Manager
Anna Wilhelm
Advocacy
Alix Weldon
Research
students
(Ph.D and
M.Sc.)
DFID Project
Manager
Dr. Lynsey Blair
Modeller,
Ethiopia and
Yemen manager
Michael French
Programme
Manager
Dr Giuseppina
Ortu
(Rwanda, Burundi)
Programme
Managers
Narcis Kabatereine
Fiona Fleming
(Uganda , Malawi
Zambia)
Advocacy
Membership of WHO Scientific and Technical Advisory Group
(STAG)
Director of UK Coalition (Wendy Harrison)
London Centre (partners)
APPMG (Author of NTD report)
ENDFUND (Technical Advisory Board)
Publications and Teaching
• Approximately 100 publications have been published or
are in press in 2005-2011 (list available)
• Staff teach in B.Sc. Module (Life Sciences) and BioMedical Sciences
• B.Sc. For 4th medical students (Hepatology and Global
health)
• M.Sc. course at Imperial College London
• Short course on Global Health at Imperial College (this
week !)
• Supervise several B.Sc. and M.Sc. students with their
projects
To achieve elimination
• Improved education and coverage
especially in “difficult countries”
• Water and sanitation
• Reduction in poverty
• Socio-economic development
Proportion of PC for schistosomiasis, soil-transmitted helminthiases, lymphatic
filariasis, onchocerciasis and trachoma, 2011
Population requiring preventive chemotherapy
~ 243 million
~ 873 million
~ 1 410 million
~ 127 million
~ 281 million
77.1
80%
60%
50%
40%
41.8
Proportion, %
70%
31.1
30%
13.3
13.7
20%
10%
Schistosomiasis
2011
# of counties reported
# of people treated
Coverage (%)
Soil-transmitted
helminthiases
Lymphatic
filariasis
Onchocerciasis
2010
2009
2008
2007
2006
2005
2011
2010
2009
2008
2007
2006
2011
2010
2009
2008
2007
2006
2011
2010
2009
2008
2007
2006
2011
2010
2009
2008
2007
2006
0%
Trachoma
Schistosomiasis
Soil-transmitted
helminthiases
Lymphatic
filariasis
Onchocerciasis
Trachom
a
24
63
34
28
ND
28,140,136
302,523,800
557,434,305
98,089,495
ND
10.4
30.6
39.5
77.1
ND
Where we are now
Where we can get with
Where we can get with
existing tools and strategies new tools and strategies
Diseases Targeted For Elimination
Guinea worm
Leprosy
Lymphatic filariasis
Blinding trachoma
Sleeping sickness
Diseases Targeted For Control
Schistosomiasis
River blindness
SoilTransmitted
Helminthes
Chagas
Visceral
Leishmaniasis
2020
Goals
Acknowledgements
To the SCI staff, past and present
To Sir Roy Anderson who has chaired the Advisory
Board annually since we started
To Professor Elio Riboli and Neil Ferguson for their
support
DIDE administrator Ruth Tipples
To all our partners especially in Liverpool.
In country - among many others
• In Uganda - Drs. Narcis Kabatereine, Edridah Tukahebwa and
the VCD staff; Dr. Sam Zaramba
• In Tanzania – Drs. Ursuline Nyandindi, Mweli Malacela, Peter
Kilima, Upendo Mwingira
• In Zanzibar - Dr. Khalfan Mohammed;
• In Zambia – Dr. Mutale Nsakashalo
• In Niger – Drs. Amadou Garba, Ali Djibo
• In Rwanda – Drs Irenee Umulisa, Corine Karema
• In Burundi – Drs Dismas Baza; Jean-Paul Nyarushatsi; Onésime
Ndayishimiye; Ndyabanirwa Janvier; Didace Mbaririmbanyi
• In Senegal – Dr Idrissa Talla
• In Ethiopia – Mr Oumer Shafi
• In Yemen – Dr Dhekra Annuzaili
• In Malawi – Dr Samuel Jemu
• In Cote D’Ivoire – Dr Aboulaye Meite, Professor Elizier N’Goran
• And WHO staff of NTD Department