Mitosis Flash Cards Ch 4 Why do cells divide rather than continuing to grow indefinitely? -The larger the cell becomes, the more demands it places on the DNA -The cell has trouble moving enough nutrients and wastes across the cell membrane Surface area to volume What limits the ratio maximum size a cell can get? What is cell division? The process by which 2 new cells are produced from one cell. What are the 4 phases of the cell cycle? 1. G1 Phase 2. S Phase 3. G2 Phase 4. M Phase 1. Cell Growth – the cell increases in size What happens during the G1 Phase? 2. synthesizes new organelles. 3. Normal cell functions What happens during DNA Replication the S Phase? What happens during Additional cell growth the G2 phase? What happens during Mitosis and Cytokinesis - Cell division occurs the M phase? What is Chromatin? DNA that is completely unwound “Spaghetti form” of DNA found during G1 of Interphase During what phase of the cell cycle does cell growth occur? Interphase (G1) What are the three parts G1, S, and G2 phases of Interphase? What is mitosis? The division of the nuclear material (nucleus) What are sister chromatids? How are the two sides of sister chromatids joined together? What are the building blocks of DNA? (Monomer) 2 identical copies of a chromatid that have been replicated and connected together centromere Nucleotides - Prophase - Metaphase - Anaphase - Telophase What are the four phases of Mitosis? What happens during Prophase? -The nucleolus and nuclear membrane “break up” and temporarily disappear. - Centrioles duplicate and separate to opposite sides of the cell. -The spindle fibers begin to form near the centrioles. What happens during Metaphase? -The chromosomes line up across the center of the cell along the equator. - Microtubules attach to the centromere of each chromosome from both poles of the spindle. What happens during Anaphase? -The spindle fibers shorten. -The centromeres are broken and the sister chromatids separate. -The chromosomes continue to move until they have separated into two groups near the poles of the spindle. What happens during Telophase? -The nuclear envelope reforms around the chromosomes. - a nucleolus becomes visible in each daughter nucleus -Chromosomes begin to unwind back to chromatin. -The spindle breaks apart. What is a histone? The protein that DNA coils around to start condensing to fit inside the nucleus What happens during cytokinesis for animal cells? - The cell membrane is pinched inward until the cytoplasm is separated into nearly equal halves. What happens during cytokinesis for plant cells? - A cell plate is formed in the center of the cell and grows outward to separate the two cells. What is the major - mitosis is asexual function of mitosis for reproduction so a new unicellular organisms? organism is created. 1. Mitosis increases the What is the major function of mitosis for number of cells multi-cellular organisms? 2. help the organism grow 3. replace dying cells. What is this phase and what is happening? Interphase G1, S, G2, •Cell growth, normal cell functions, and replication of DNA and organelles. What is this phase and what is happening? Prophase -The nucleolus and nuclear membrane “break up” and temporarily disappear. - Centrioles duplicate and separate to opposite sides of the cell. -Sister chromatids are held together by centromeres -The spindle fibers begin to form near the centrioles. What is this phase and what is happening? Metaphase -The sister chromatids line up across the center of the cell (equator) - Spindles attach to the centromere of each chromosome from both poles of the spindle. What is this phase and what is happening? Anaphase What is this phase and what is happening? Telophase -The nuclear envelope reforms around the chromosomes. -Chromosomes begin to unwind back to chromatin. - a nucleolus becomes visible in each daughter nucleus -The spindle breaks apart. -The centromeres are broken and the sister chromatids separate. -Spindle fibers shorten -The chromatids continue to move until they have separated into two groups near the poles of the spindle. What is the role of the mitotic spindle (spindle fibers) in mitosis? To line up and divide the chromosomes What is the role of the centrioles in animal cells? To divide the chromosomes during mitosis