Grade 9 BIOLOGY THE NERVOUS SYSTEM WHAT DOES YOUR NERVOUS SYSTEM DO? Your ideas: Hear what Tim and Moby have to say... WHAT IS PART OF THE NERVOUS SYSTEM? ORGANIZATION OF THE NERVOUS SYSTEM How many neuron connections do you have? How is the nervous system divided up? What are major parts of the nervous system…? WHAT DO NEURONS LOOK LIKE? Label a neuron! MAJOR TYPES OF NEURONS Differences: Motor Similarities: Sensory HOW DO NEURONS SEND A SIGNAL? ELECTROCHEMICAL CHANGE that moves in one direction along a neuron involves changes in voltage (charge) as well as in the concentrations of ions What charge does a cell have at rest? Slightly negative WHY? Remember… what does the sodium/potassium pump do? Review of the Na+ / K+ pump Na + K+ The inside of the cell is negative because: More positive ions are pumped out of the cell than into the cell (3 Na+ out / 2 K+ in) Negatively charged proteins already in the cell Some K+ ions leave through potassium channels ACTION POTENTIAL Review: Change in the relative charges inside and outside the cell because of changes in ion concentration How do polar molecules get across membranes? In the cell membrane there are two types of gated ion channels (they open and close): Na+ channels K+ channels There are also Na+/K+ pumps HOW DOES IT WORK? Questions: Where is there more Na+? Inside or outside the cell? Where is there more K+? Inside or outside the cell? What do we need to do to make the inside of the cell change from negative to positive? Na + K+ STEPS IN AN ACTION POTENTIAL 1. Resting potential Na+ outside, K+ inside Channels closed 2. Stimulus / Threshold Some Na+ channels open Na+ comes in If threshold is passed First... Watch the tutorial animation! they all open 3. Depolarization Na+ channels open, Na+ comes in and the cell becomes positive Chain reaction of Na+ channels opening down the axon 4. Repolarization Na+ channels close, K+ channels open K+ moves out and the cell becomes negative STEPS IN AN ACTION POTENTIAL 5. Undershoot First... Watch the tutorial animation! K+ leaves as K+ channels slowly close Cell is MORE negative than usual 6. Return to Resting Potential Both Na+ and K+ channels close Na+ / K+ pump returns Na+ and K+ to the right places Na+ K+ Na+ K+ Na+ channels open, 3 Additional + K channels are closed; interior of cell becomes more positive. Na+ 4 Na+ channels+ close and inactivate. K channels open, and K+ rushes out; interior of cell more negative than outside. Action potential 3 2 Threshold potential Na+ 2 A stimulus opens some Na+ channels; if threshold is reached, action potential is triggered. Neuron interior 1 Resting potential 4 5 + 5 The K channels close relatively slowly, causing a brief undershoot. 1 Neuron interior state: voltage gated Na+ 1 Resting + and K channels closed; resting potential is maintained. 1 Return to resting state. Another look at an action potential! COMPLETE AND KNOW THIS CHART… Steps in an Action Potential Where is Na+ ? Where is K+ ? Na+ channels? K+ channels? What charge is inside? What charge is outside? Resting Potential Depolarization Repolarization Undershoot Return to Resting Potential COMPLETE AND KNOW THIS CHART… Steps in an Action Potential Resting Potential Where is Na+ ? Outside Where is K+ ? Inside Na+ channels? Closed K+ channels? Closed What charge is inside? Negative What charge is outside? Positive Depolarization Repolarization Undershoot For example… This is Resting Potential Return to Resting Potential WHAT DOES THE MYELIN SHEATH DO? Watch here! With the myelin sheath you... Only trade ions in the Nodes of Ranvier instead of all along the axon = faster signal along the axon! Multiple Sclerosis (MS) happens when you lose your myelin sheath neurons can’t send messages fast enough! WHAT IS A REFLEX? A Reaction Time is... How fast you can react to something Uses your brain! (catching a ball, saving a goal) A Reflex is... An automatic reaction that does NOT use your brain Message goes to the spinal cord and back only (moving your hand away from something hot) THE KNEE-JERK REFLEX...