HAPPY MONDAY Bellwork: In 30 words, describe the structure of DNA (what is it made of). If possible, describe what it does and how it does it. *use your biomolecule chart?* DNA & Replication Notecards Pre-AP Biology Due Tuesday (10/14/14) DNA Nucleotide Nucleic Acid Deoxyribose Nitrogenous Base Hydrogen Bond Adenine Cytosine Guanine Thymine Purine Pyrimidine Double Helix Antiparallel Semi-Conservative DNA Polymerase Helicase DNA Replication Complementary Strand Essential Question: What are the components of DNA? A lesson from Jurassic Park... The nucleic acids we’ll talk about in biology are DNA and RNA Deoxyribonucleic acid = DNA DNA is the biomolecule used to pass on genetic information to the next generation. So…your DNA is half mom, half dad! Oswald Avery discovered that the nucleic acid DNA stores and transmits the genetic information from one generation to the next. DNA is a long molecule made up of nucleotides. Each nucleotide is composed of a 5-carbon sugar called deoxyribose, a phosphate group, and a nitrogenous base. Phosphate Group = has phosphorus = P Nitrogenous Base = has nitrogen = N The monomer of DNA is called a nucleotide, which has: 1. 5-carbon sugar (deoxyribose) 2. phosphate group 3. nitrogenous base. This means that the elements in a nucleic acid are: C, H, O, N, and P DRAW AND LABEL There are 4 kinds of nitrogenous bases in DNA. Adenine, Guanine, Cytosine, & Thymine The backbone of a DNA chain is formed from the sugar and phosphate groups of each nucleotide. Nucleotides can be joined together in any order. The observation that [A] = [T] and [G] = [C] became known as Chargaff’s rule. In a strand of DNA, adenine and thymine pair together while cytosine and guanine pair together. This pairing of bases is known as base pairing. The differently shaped bases are bonded together antiparallel to one another (5’3’) Sage and Scribe Can you draw a picture of DNA using 6 nucleotides? Watson and Crick discovered the true shape of DNA. The shape of DNA is a double helix. A double helix looks like a twisted ladder or a spiral staircase. DNA molecules in prokaryotic organisms are found in the cytoplasm. The DNA molecule in a prokaryotic organism is circular in shape. Eukaryotic organisms possess 1000X more DNA than prokaryotic organisms. Eukaryotic DNA is generally located in the nucleus in the form of chromosomes. All eukaryotic organisms do not carry the same number of chromosomes. Chromosomes are not clearly visible during most of the cell cycle. When the DNA is “unraveled” and doing its job, it is known as chromatin. However, during mitosis (M phase), the chromatin coils and condenses to form chromosomes. Important to Remember: All living things have DNA! Scientists refer to this as a “common genetic code” The sequence of bases matters! The order determines the organism. Think-Pair-Share: How do you think DNA copies itself?