Standard 2A: Macromolecules Warm-up 10/08 • What are the 2 macromolecules shown here? • What is a function of each? Protein • • • • • Cell Structure Movement/Transport Enzymes Regulatory Defense Nucleic Acid • Genetic Information Storage • Genetic Information Transfer Agenda 10/07 • Standard 2A Review • Hand in Mini-Poster 2A Standard Test Topics • Macromolecules – Structure and Function – Carbohydrates – Lipids – Proteins – Nucleic Acids Macromolecule Review • Share your Mini-Macro Poster with three other people that did not have your same macromolecule. • Fill-in Review Chart • Flash Cards • Macromolecule Video – http://youtu.be/H8WJ2KENlK0 Warm-up 10/08 • One more time. Which is what? A C B D Agenda 10/08 • Video Review (start at 3:35) • Standard 2A Macro Mini-Poster p.13 You will be graded on providing all of the following information about your macromolecule. This information must be somewhere on your poster. • • • • • What is your macromolecule made out of? (be VERY specific) What are some different types of your macromolecule? What are some examples of your macromolecule? How does that macromolecule apply to your life? (Be VERY specific) What would happen to a person who did not have, or could not use, your macromolecule? • What are two interesting facts about your macromolecule? • Include a diagram or picture of your molecule. • Write 2 quiz questions on your macromolecule (on a separate piece of paper) Warm-up 10/07 1. 2. 3. 4. Which of the following is a carbohydrate? Which is a Protein? Which is a Lipid? B How do you know? OH C A Agenda 10/17 • Protein Quizzle • Nucleic Acids – Structure – Answers pp. 12-13 • HW- Review pp. 14-15 Due Tomorrow • STANDARD 2 Thursday Nucleic Acids • http://www.biotechnologyonline.gov.au/popups/int _dnazoom.html • A closer look… – http://www.pbs.org/wgbh/nova/genome/dna_flash.html • Can you build DNA? – http://learn.genetics.utah.edu/content/begin/dna/buildd na/ Nucleic Acids CHONP One Strand of DNA phosphate • The backbone of the molecule is alternating phosphate and a sugar, deoxyribose. • The teeth are nitrogenous bases. sugar Nitrogen base Nucleic Acid Structure DNA RNA Nucleic Acids p.12 NUCLEIC ACIDS carry the genetic • _______________ information in a cell. DNA or DEOXYRIBONUCLEIC ACID contains ______________________________ all the instructions for making every protein RNA copies and needed by a living thing. _____ transfers this genetic information so that proteins can be made. The subunits that make up nucleic acids are called NUCLEOTIDES _______________. STRUCTURE Nucleotide (3 sub units) Nitrogenous base (A, G, C, or T) Phosphate Group P CH2 O N C C Sugar (deoxy-ribose) C C Nucleic Acid Questions p. 13 1. Nucleic acids carry __________ GENETIC information in a molecule called _____ DNA or DEOXYRIBONUCLEIC acid. _____________________ 2. DNA has the instructions for making a cell's PROTEIN __________. RNA copies DNA so 3. The nucleic acid _____ PROTEINS can be made. ___________ NUCLEOTIDES are the subunits making up 4. _____________ nucleic acid. Nucleic Acid Questions p. 13 5. The 3 parts of a nucleotide are a 5 carbon _________, a phosphate, and a nitrogen SUGAR _______. BASE ATP is a high energy molecule made from a 6. _____ NUCLEOTIDE with THREE ______________ _______ phosphates. Building DNA • Bonds can be made by – Find the 5’ carbon on the deoxyribose sugars of the template strand. – Build the complementary strand by matching nucleotides to the template strand. – Notice they will be anti-parallel configuration of template and complementary strands. – Match the complimentary base pairs (hydrogen bonds) that enable replication and error correction. • Required macromolecules – 1 DNA strand (choose a template and create it’s complementary strand) Warm-up 10/08 Which is what? B A CARBOHYDRATE NUCLEIC ACID C D LIPID PROTEIN Agenda • Review Check pp. 14-15 • Macro Review • Macro Bingo • 2A Standard Tomorrow 10/10 Packet Cover: What is this? Function? 2A Review p. 14 1. Give the symbols for the elements that make up each of the following: CHO CHONP _____carbohydrates ______lipids _________DNA CHOP ______ CHON proteins 2. Name the 4 classes of macromolecules & give a function for each. a. Carbohydrates- sugar , starch, cellulose, glycogen b. Lipids- phospholipid, triglyceride, cholesterol c. Protein- enzymes, collagen, keratin d. Nucleic Acid- DNA, RNA 2A Review p. 14 3. Name the subunits that make up each of the macromolecules. monosaccharide CarbohydratesLipids- Fatty acids DNA- nucleotides Proteins- Amino acids 4. Enzymes can be denatured (unfolded) by what environmental factors? Heat and pH 5. What process is used to link amino acids together? Dehydration or condensation reaction (removal of water) 2A Review p. 14 6. Name the bonds found between amino acids in a polypeptide chain._________ peptide 7. Explain the difference between a disaccharide and a polysaccharide. Give an example of each. Disaccharide – 2 monosaccharides ; sucrose, lactose Polysaccharide – many monosaccharides ; starch, cellulose, glycogen, 8. What two functional groups are found in amino acids? Amino - NH2 and Carboxyl or Acid - COOH 2A Review p. 14 9. Why are enzymes important to organisms? The control and regulate chemical reactions, often speeding up the process 10. What is the difference between a saturated and unsaturated fatty acid? Saturated fats have all single bonds between the carbons, they are solid at room temperature and found in animal fat. Unsaturated fats have one or more double bonds between the carbons, they are liquid at room temperature and found in plants. Major Class Carbohydrates CHO (C H2 O)n n= number of Carbon Functions -energy -structure Subclass Monosaccharide (monomer) Disaccharides Polysaccharides (polymer) Examples Identifying Features Fructose Glucose 1 ring Sucrose 2 rings Starch Glycogen Cellulose Chitin Many rings, Branched or Stacked, linked Major Class Subclass Examples Identifying Features Lipids CHO FATS Long chains ENERGY Saturated or unsaturated, Fatty acids, Triglycerides Polar Head CHOP Cell membrane Phospholipids two nonpoloar tails All are non-polar (hydropholic) Major Class Subclass Examples Identifying Features Proteins CHON Enzymes Support Reactions Movement Transport Defense Amino Acids (monomers) 20 Types Polypeptides (polymer) Enzymes collagen Hormones Keratin NH2 – Amino Group COOH – Acid Major Class Nucleic Acids CHONP Nucleotide: Sugar, Phosphate, and Nitrogen Base Subclass DNA Examples Genetic information RNA Transfer of Genetic information Macro Bingo • • • • • • • • • • Carbohydrate Amino acid Cholesterol Cellulose Fat Enzyme DNA Lipid Hydrophobic hydrophilic • • • • • • • • • • Glycogen Unsaturated Organic compound Peptide bond Saturated Phospholipid Polymer Starch Polysaccharide Monomer • • • • • • • • • • Polypeptide Nucleic acid Nucleotide Protein Steroid Monosaccharide Disaccharide Atomic # Covalent Bond Atomic Mass The Molecules of Cells • The Molecules of Cells You are what you eat. • http://www.youtube.com/watch?v=H8WJ2KE NlK0 Macromolecules Similarities among all types of cells • All cells use nucleic acids to store and access information (DNA & RNA) • All cells use proteins as catalysts (enzymes) for chemical reactions • All cells use lipids for membrane components • All cells use carbohydrates for energy source and in cell walls • You are what you eat! – http://youtu.be/H8WJ2KENlK0 What are Macromolecules? • Biologically important macromolecules are “polymers” of smaller subunits Macromolecule Subunit Polymer Monomer Carbohydrates Proteins Nucleic acids : : : monosaccharide (sugar) amino acids nucleotides Where do these subunits come from? • Converted in Photosynthesis or Chemosynthesis • Metabolism • Recycled from old cells LUCA (Last Universal Common Ancestor)