Frederick Griffith Oswald Avery, Maclyn McCarty, and Colin MacLeod Alfred Hershey and Martha Chase Rosalind Franklin and Maurice Wilkins Alfred Hershey and Martha Chase Alfred Hershey and Martha Chase DNA Structure Protein Synthesis - Overview The DNA of the gene is transcribed into RNA Which is translated into protein The flow of genetic information from DNA to RNA to Protein is called the CENTRAL DOGMA DNA RNA Protein Nucleus Protein Synthesis - Overview Transcription Polypeptide Cytoplasm DNA RNA Protein mRNA Translation DNA Protein Synthesis (Overview) Central Dogma - FLOW IS FROM DNA TO RNA TO PROTEIN Protein Synthesis (Overview) FLOW IS FROM DNA TO RNA TO PROTEIN Genes on DNA are expressed through proteins, which provide the molecular basis for inherited traits A particular gene, is a linear sequence of many nucleotides The gene specifies a polypeptide (long protein made of amino acids) Protein Synthesis (Overview) Genes - discrete units of hereditary information comprised of a nucleotide sequence found in a DNA molecule. ANIMATIONS DNA Replication (Real Time) Harvard DNA Replication - enzyme explanations DNA Replication – short DNA Transcription - DNA to RNA Translation in the Cytoplasm - RNA to Protein Translation - Step by Step DNA Replication DNA Replication tRNA and Binding of Amino Acids to tRNA Translation – RNA to polypeptide tRNA pre mRNA mRNA ribosome Exon Word Bank: RNA Polymerase Nucleus translation anticodon intron Protein Synthesis transcription amino acids codons growing polypeptide DNA