Biology Introduction Understand your world Make informed decisions Self Family Medical Diet Make informed votes Understand significance of accomplishments Bios = life ology = study of Biology = study of life Organization Atom Molecule Cell Tissue Organ Organ system Organization (cont.) Multicelled organism Population Community Ecosystem Biosphere Acquire energy Autotrophs Heterorophs Metabolize Maintain homeostasis Grow Reproduce Respond Adapt Taxonomy—ID and organize into logical groups Nomenclature—name organisms Binomial nomenclature (Genus, species) Homo sapiens Canis lupus Felis concolor Domain Kingdom Phylum Class Order Family Genus Species Eukarya Animalia Arthropoda Insecta Lepidoptera Danaidae Danaus plexippus Monarch Butterfly Eubacteria Archaebacteria Eukarya Kingdom Protista Kingdom Fungi Kingdom Plantae Kingdom Animalia Gather information about the world Do it objectively Explain the natural world using rules or patterns in the natural world Explanations that are testable Can use information for prediction No conclusion drawn in science is final! However, can say many things with high probability Observation Hypothesis Test Analyze Repeat Theory & Interpret Control Group Standard of Comparison Identical to testing group other than the variable being tested Sampling Error Certain amount of error in any study Try to minimize by taking large sample sizes Observation: Some students fall asleep in Dr. Bern’s class Hypothesis: Dr. Bern is the most boring Biology instructor Test: Count number of sleeping students in Dr. Bern’s and Mr. Harnden’s classes Results: 3/48 Students sleeping in Dr. Bern’s class, 4/48 students sleeping in Mr. Harnden’s class Repeat: Count sleeping students in Dr. Bern’s and Ms. Henderson’s classes Results: 3/48 students sleeping in Dr. Bern’s class, 2/48 students sleeping in Ms. Henderson’s Analysis: 4% of students sleep in Ms. Henderson’s class, 6% in Dr. Bern’s, 8% in Mr. Harnden’s. There is a 3% margin of error. Conclusion: Student’s sleep in Dr. Bern’s class at the same rate as other Biology instructors Theory: Whether or not students fall asleep in class doesn’t depend on the instructor Can we use viruses that attack bacteria (bacteriophages) to fight infections? Hypothesis - Bacteriophages can protect mice against infectious bacteria Prediction - Mice injected with bacteriophages will not die as a result of bacterial injection Experimental Inject with bacteria and bacteriophage Control group group Inject with bacteria and saline Experimental group All mice lived Control group All mice died Conclusion - Bacteriophage injections protect mice against bacterial infections Prediction - Bacteriophage injections will be more effective treatment than single dose of the antibiotic streptomycin Test - Mice injected with bacteria, then with saline, streptomycin, or bacteriophage With 2nd injection: Bacteriophage - 11 of 12 mice lived 60 mg/gm streptomycin - 5 of 12 lived 100 mg/gm streptomycin - 3 of 12 lived Saline - all mice died Conclusion - Bacteriophage treatment can be as good or better than antibiotic Limited to our knowledge and understanding of the natural world Cannot answer philosophical, moral, or ethical questions Limited by man’s falibility