Reading Log Procedures Grab a text book Reading Log- Week (i.e. 1/11-1/15) Date Write out essential question and page numbers Respond in no less than 5 complete sentences Reading Log Grading 100 Points 80 Points The response indicates The response indicates that the student has a that the student has a complete understanding partial understanding of of the reading concept. the reading concept. The response is Not all aspects of the accurate, complete, and question are addressed, is fully supported by or response is not information from the rooted or derived from text. the text. 50 Points The response is inaccurate, confused, and/or irrelevant. The student has failed to respond to the task. The Nervous System CHAPTER 7 Objectives To explain the main components of the nervous system. To compare and contrast the central nervous system and the peripheral nervous system. To differentiate between the somatic and autonomic nervous systems. Nervous System Think back to when we talked about nervous tissue. What is it’s function? How does it go about doing this? General Functions: ◦ Sensory (detect change) ◦ Integrative (make sense of it) ◦ Motor (cause a response) Functions of the Nervous System gather information response of muscles/organ Figure 7.1 CNS vs. PNS CNS (Central Nervous System): ◦ Brain ◦ Spinal Cord PNS (Peripheral Nervous System): ◦ Cranial nerves ◦ Spinal Nerves PNS Contains a sensory division and a motor division. Sensory Division: ◦ Contains sensory receptors that convert info into a nerve impulse and transmit it back to the CNS to make sense of it. ◦ Monitors environmental changes such as light and sound ◦ Detects changes in homeostasis ( ex: temperature, oxygen level) Motor Division Utilize peripheral neurons to carry impulses from the CNS to an effector which will cause a response ◦ Ex: muscle contraction, gland secretion, etc. Motor Division Somatic Nervous System: ◦ Controls skeletal muscle and voluntary movement. Autonomic Nervous System: ◦ Controls effectors that are involuntary ◦ Ex: heart, smooth muscle, certain glands Lets put that all together… 1. Turn in Stimulus Response Lab 2. Begin working on reading log Reading Log- Week (i.e. 1/11-1/15) Date Write out essential question and page numbers Respond in no less than 5 complete sentences Reading Log Grading 100 Points 80 Points The response indicates The response indicates that the student has a that the student has a complete understanding partial understanding of of the reading concept. the reading concept. The response is Not all aspects of the accurate, complete, and question are addressed, is fully supported by or response is not information from the rooted or derived from text. the text. 50 Points The response is inaccurate, confused, and/or irrelevant. The student has failed to respond to the task. Objectives To identify the basic structure and classification of neurons. Nervous Tissue Two Principal types of cells: ◦ Neurons (nerve cells)- transmit nerve impulses from one part of the body to another ◦ Neuroglia (or simply glial cells)- supporting cells of nervous tissue ◦ Protect, support and insulate neurons ◦ Ex: Astrocytes, Microglia, Ependymal Cells, Oligodendrocytes, Schwann Cells Structure of a Neuron Reacts to physical/chemical changes in surroundings Transmit information through nerve impulses to other neurons and other cells. Structure of a Neuron Label using the diagram on pg 233 Neuron Structures Axon Node of Ranvier Axon terminals Nucleus Cell body Schwann cells Dendrites Synaptic Cleft Myelin sheath Neuron Structures Axon - the long extension of a neuron that carries nerve impulses away from the body of the cell. Axon terminals - the hair-like ends of the axon; release neurotransmitters into synaptic cleft Cell body - the cell body of the neuron; it contains the nucleus (also called the soma) Dendrites - the branching structure of a neuron that receives messages and send to cell body(attached to the cell body) Myelin sheath - the fatty substance that surrounds and protects some nerve fibers Node of Ranvier - one of the many gaps in the myelin sheath - this is where the action potential occurs during saltatory conduction along the axon Nucleus - the organelle in the cell body of the neuron that contains the genetic material of the cell Schwann cells - cells that produce myelin - they are located within the myelin sheath. Synaptic Cleft- gap between axon terminals of one neuron and the dendrites of another EQ: How does a nerve impulse travel down a neuron? Pgs 237-239 (1 column) st Reading Log- Week (i.e. 1/11-1/15) Date Write out essential question and page numbers Respond in no less than 5 complete sentences Objectives To explain how a nerve impulse occurs. To explain different things that inhibit an action potential. To understand components of a neuron that contribute to impulse velocity. I. Stages of a Nerve Impulse 1. Resting Neuron a. b. polarized = more (+) ions outside nerve cell than inside. SALTY Resting potential = -70 mV (potential= difference) BANANA Na+ K+ Na+ I. Stages of a Nerve Impulse 2. Depolarization a. influx of sodium (Na+) b. initiates an action potential c. “all-or-none” response: -50 mV 3. Repolarization a. Peaks at +30 mV b. exit of K+ ions +30 4. Initial Conditions Restored a. Na+/ K+ Pump- Restores initial concentrations of Na+ and K+ 3 Na+ pumped out 2 K+ Pumped in USES ATP Let’s Simulate it! I need 3 volunteers! ◦Na+ Channel x 2 ◦K+ Channel x 1 ◦Na+/K+ Pump x 1 EQ: What are the components of a reflex arc? Pg 240 Reading Log- Week (i.e. 1/11-1/15) Date Write out essential question and page numbers Respond in no less than 5 complete sentences Objectives To understand components of a neuron that contribute to impulse velocity. To understand the synaptic communication between neurons To examine the components of a reflex arc Figure 7.9 The nerve impulse. [Na+] [K+] Na+ + Slide 3 (a) Resting membrane electrical conditions. The external face of the membrane is slightly positive; its internal face is slightly negative. The chief extracellular ion is sodium (Na+), whereas the chief intracellular ion is potassium (K+). The membrane is relatively impermeable to both ions. (b) Stimulus initiates local depolarization. A stimulus changes the permeability of a “patch” of the membrane, and sodium ions diffuse rapidly into the cell. This changes the polarity of the membrane (the inside becomes more positive; the outside becomes more negative) at that site. Figure 7.9 The nerve impulse. [Na+] [K+] Na+ + (a) Resting membrane electrical conditions. The external face of the membrane is slightly positive; its internal face is slightly negative. The chief extracellular ion is sodium (Na+), whereas the chief intracellular ion is potassium (K+). The membrane is relatively impermeable to both ions. (b) Stimulus initiates local depolarization. A stimulus changes the permeability of a “patch” of the membrane, and sodium ions diffuse rapidly into the cell. This changes the polarity of the membrane (the inside becomes more positive; the outside becomes more negative) at that site. Na+ + Slide 4 (c) Depolarization and generation of an action potential. If the stimulus is strong enough, depolarization causes membrane polarity to be completely reversed and an action potential is initiated. Figure 7.9 The nerve impulse. Slide 6 (d) Propagation of the action potential. Depolarization of the first membrane patch causes permeability changes in the adjacent membrane, and the events described in (b) are repeated. Thus, the action potential propagates rapidly along the entire length of the membrane. + K+ (e) Repolarization. Potassium ions diffuse out of the cell as the membrane permeability changes again, restoring the negative charge on the inside of the membrane and the positive charge on the outside surface. Repolarization occurs in the same direction as depolarization. Figure 7.9 The nerve impulse. Slide 7 (d) Propagation of the action potential. Depolarization of the first membrane patch causes permeability changes in the adjacent membrane, and the events described in (b) are repeated. Thus, the action potential propagates rapidly along the entire length of the membrane. + (e) Repolarization. Potassium ions diffuse out of the cell as the membrane permeability changes again, restoring the negative charge on the inside of the membrane and the positive charge on the outside surface. Repolarization occurs in the same direction as depolarization. K+ Cell exterior Na+ Diffusion Na+ Na+ Na+ K+ Na+ Cell interior K+ K+ + K+ K Na+ Na+ – K+ pump (f) Initial ionic conditions restored. The ionic conditions of the resting state are restored later by the activity of the sodium-potassium pump. Three Plasma membrane sodium ions are ejected for every two potassium ions carried back into the cell. Myelin Sheaths ◦ Whitish, fatty material wrapped jelly-roll style around the axon ◦ Produced by schwann cells outside CNS (oligodendrocytes in CNS) Saltatory Conduction 1. “Jumping” of nerve impulse 2. Myelinated FASTER than unmyelinated nerves Multiple Sclerosis (MS) Individuals with multiple sclerosis (MS), experience destruction of their myelin sheath. How would this affect the transmission of an impulse? What symptoms would you expect to see? II. SYNAPTIC COMMUNICATION * Synapse = gap (space) between neurons Sequence of Events at Synapse 1. Arrival of nerve impulse (action potential) Axon of transmitting neuron Axon terminal Action potential arrives Vesicles Synaptic cleft Receiving neuron Synapse Text p. 240 Figure 7.10 2. Diffusion of Neurotransmitter (into synapse) Examples: a. adrenaline b. acetylcholine c. serotonin 3. Post-Synaptic Activation (of next neuron) Neuromuscular Junction Review : Transmission of a Signal at Synapses (Fig 7.10) Axon of transmitting neuron Axon terminal Action potential arrives Vesicles Synaptic cleft Receiving neuron Synapse Transmitting neuron Vesicle fuses with plasma membrane Neurotransmitter binds to receptor on receiving neuron’s membrane Neurotransmitter is released into synaptic cleft Neurotransmitter molecules Synaptic cleft Ion channels Receiving neuron Neurotransmitter broken down and released Neurotransmitter Receptor Na+ Na+ Ion channel opens Ion channel closes Figure 7.10 CLINICAL APPLICATIONS 1. PARKINSON’S DISEASE: LOW DOPAMINE in brain 2. DEPRESSION: LOW SEROTONIN LEVELS Reflexes Ordinarily, a receptor sends a signal to the brain where the brain coordinates a response. What happens when you touch something hot? Reflex Arc A reflex is a rapid action that happens without thought and does not involve the brain. Lets take a look… ◦ http://www.bbc.co.uk/schools/gcsebitesize/science/aqa_pre_2011/human/t henervoussystemrev3.shtml Reflex Arc 1) Receptor- sense organ in skin, muscle, or other organ 2) Sensory Neuron- carries impulse towards CNS from receptor 3) Interneuron- carries impulse within CNS 4) Motor Neuron- carries impulse away from CNS to effector 5) Effector- structure by which animal responds (muscle, gland, etc). Reflex Arc Types of Reflexes Babinski Reflex